Everest Medicines Acquires Exclusive Greater China and Other Asian Country Rights to VIS-101, a Novel Bifunctional Biologic for Serious Eye Disorders ACN Newswire

Everest Medicines Acquires Exclusive Greater China and Other Asian Country Rights to VIS-101, a Novel Bifunctional Biologic for Serious Eye Disorders

HONG KONG, Oct 30, 2025 - (ACN Newswire via SeaPRwire.com) – Everest Medicines (HKEX:1952.HK) today announced that it has acquired an exclusive license with Visara, Inc. (“Visara”), a subsidiary of NovaBridge Biosciences (formally known as I-Mab, and is a company listed on the Nasdaq Global Market trading under the symbol “NBP”), to secure an exclusive license to develop, manufacture and commercialize VIS-101, in Greater China, Singapore, South Korea and certain Southeast Asian countries.This collaboration marks Everest’s strategic expansion into ophthalmology, a high-potential “blue-ocean” therapeutic area, further enriching its late-stage product pipeline and strengthening synergies across its core therapeutic portfolio.Under the assigned exclusive license, Everest Medicines will make an upfront payment of US$7 million (equivalent to approximately RMB49.7 million) and reimburse up to RMB24.0 million for prior expenses; and pay up to US$89.0 million (equivalent to approximately RMB632.0 million) in potential milestones; plus tied royalties on net sales.“We are pleased to collaborate with Visara. This partnership brings a highly differentiated and commercially attractive asset to Everest’s late-stage product pipeline and marks our entry into ophthalmology, a competitively attractive therapeutic area with significant unmet medical needs,” said Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines. “Leveraging Everest’s clinical development and commercialization expertise, we look forward to advancing VIS-101, a potential best-in-class bifunctional antibody, towards commercialization in China and across Asia.”VIS-101 is a novel bifunctional biologic targeting VEGF-A and ANG-2 that is more potent and could potentially provide more durable treatment benefits than existing treatments for patients with wet age-related macular degeneration, diabetic macular edema, and retinal vein occlusion. VIS-101 has completed initial safety and dose-escalation studies in both the United State of America and China, and is currently completing a randomized, dose-ranging Phase 2 study in China. VIS-101 is anticipated to be Phase 3-ready in 2026.“VIS-101 is anticipated to be second-in-class with best-in-class potential, based on bioengineered, superior target neutralizing capabilities.” said Dr. Emmett T. Cunningham, Jr, Co-Founder and Executive Chairman of Visara.Globally, the market size for anti-VEGF ophthalmic drugs reached approximately USD 23 billion in 2024 and is projected to exceed USD 40 billion by 2030. In China alone, the prevalent patient population of AMD and DME exceeds 15 million, with around 600,000 new cases each year, yet only about 500,000 patients currently receive treatment. This indicates vast market potential.Visara is a subsidiary of NovaBridge Biosciences (Nasdaq: NBP), of which Everest Medicines is currently the largest shareholder. “Licensing out Greater China, South Korea and Southeast Asia rights to Everest Medicines is an important step toward streamlining global commercial rights and creating synergy in global clinical development,” said Dr. Sean Fu, Chief Executive Officer of NovaBridge Biosciences. “We are excited to work with Everest Medicines team as a strategic partner."Under its “dual-engine” strategy, Everest Medicines has established a commercialization platform anchored by two blockbuster products targeting high-potential markets and powered by the in-house in vivo CAR-T and mRNA therapeutic cancer vaccine platforms. The Company will continue to focus on key therapeutic areas and new growth markets, with ophthalmology as the next growth driver to strengthen synergy across its core portfolio.Everest’s core product pipeline in rental diseases, infectious diseases, and autoimmune disorders has entered a critical growth stage. NEFECON® and XERAVA® have established sustainable commercial cash flow generation, while VELSIPITY® (etrasimod) is expected to become the company’s next blockbuster product. Everest continues to enhance its innovation capability and long-term competitiveness by leveraging its industry-leading mRNA therapeutic cancer vaccine platform and mRNA in vivo CAR-T platform.At a recent corporate strategy meeting, Everest Medicines announced plans to in-license more than three high-potential assets within the next 6–12 months, with an aggregate domestic peak sales potential exceeding RMB10 billion. Combined with its existing portfolio, Everest Medicines expects its total domestic peak sales potential to surpass RMB20 billion. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
雲頂新耀與Visara簽訂協議 將在大中華區及其他亞洲市場開發及商業化VIS-101 ACN Newswire

雲頂新耀與Visara簽訂協議 將在大中華區及其他亞洲市場開發及商業化VIS-101

香港, 2025年10月30日 - (亞太商訊 via SeaPRwire.com) - 10月30日,雲頂新耀宣布已與Visara簽訂協議,獲得獨家許可,在大中華區、新加坡、韓國及若干東南亞國家進行臨床開發、生產和商業化VIS-101。該合作標志著雲頂新耀正式進軍眼科這一高潛力藍海領域,豐富了公司的後期產品管線,進一步拓展其核心治療領域佈局。根據指定獨家許可,雲頂新耀將支付700萬美元(相當於約人民幣4,970萬元)的預付款,及不超過人民幣2,400萬元的自付費用報銷;最高不超過8,900萬美元(相當於約人民幣6.32億元)的潛在開發及銷售里程碑款項;以及按淨銷售額的潛在特許權使用費。雲頂新耀首席執行官羅永慶先生表示:「我們非常高興與Visara建立合作夥伴關系,此次戰略合作引入的創新藥物VIS-101兼具高度差異化與商業潛力,進一步豐富了公司的後期產品管線,並將業務拓展至眼科這一臨床需求尚未充分滿足且具有創新機會的藍海治療領域,為公司發展注入新的增長動能。未來,我們將依托公司卓越的臨床開發能力和商業化平台,高效推進VIS-101這一潛在同類最佳的雙功能生物制劑在中國及亞洲地區的臨床開發與商業化進程,盡快為患者提供這一創新治療選擇。」VIS-101是一款新型雙功能生物制劑,針對VEGF-A與ANG-2,其療效較第一代治療更為顯著,可有望為濕性年齡相關性黃斑部病變(wet AMD)、糖尿病性黃斑部水腫(DME)及視網膜靜脈阻塞(RVO)患者提供更持久的治療效益。VIS-101已於美國及中國完成初步安全性與劑量遞增研究,目前正於中國進行隨機分組的劑量範圍II期臨床試驗,預計將於2026年具備進入III期臨床試驗的條件。Visara聯合創始人兼執行主席Cunningham博士表示:「VIS-101有望成為該類別中第二款上市的藥物,並具備同類最佳(best-in-class)的潛力。這源於其在生物工程上的優異設計,使其具備更強的靶點中和能力。」目前,抗VEGF(血管內皮生長因子)療法是眼底疾病的主要治療手段,通過抑制眼內異常新生血管的生成與滲漏,從而改善視功能。2024年全球抗VEGF眼科藥物市場規模已達約230億美元,預計到2030年將超過400億美元。眼科藥物市場空間廣闊,僅在中國,wet AMD和DME的現有及新增患者人數已超過1,500萬,每年新增約60萬例,而目前接受抗VEGF治療的患者人數僅約50萬,存在巨大的未被滿足的臨床需求。Visara為新橋生物(前稱為I-Mab,納斯達克股票代碼:NBP)的附屬公司,雲頂新耀目前是新橋生物的第一大股東。新橋生物首席執行官傅希湧博士表示:「此次將VIS-101大中華區、韓國及東南亞地區的權益授權給雲頂新耀,是我們在優化全球商業佈局、推動全球臨床開發協同方面邁出的重要一步。我們期待與雲頂新耀共同推進該產品在亞洲地區的戰略協作,為更多患者帶來創新治療選擇。」此次合作是雲頂新耀在「雙輪驅動」戰略指導下的又一關鍵落子。公司正在構建以多個大單品商業化平台為基石、以自體生成CAR-T平台與mRNA腫瘤治療性疫苗平台的自主研發與臨床轉化為引擎的價值體系。未來,公司將持續聚焦優勢治療領域,引進高潛產品,進一步強化核心產品組合的協同效應。目前,雲頂新耀在腎科、感染及自身免疫性疾病等核心治療領域的產品管線已進入關鍵收獲期。耐賦康(R)與依嘉(R)已形成可持續的商業化造血能力,維適平(R)(艾曲莫德)有望成為下一個確定性大單品。在自主研發方面,公司依托領先的mRNA腫瘤治療性疫苗平台與自體生成CAR-T平台為核心,持續夯實自研技術壁壘。在近期的發展戰略交流會上,公司進一步明確未來6-12個月計劃引進3個以上的重磅產品,預計引進產品的潛在國內銷售峰值將超過人民幣100億元,疊加現有產品矩陣,整體國內銷售峰值有望突破人民幣200億元。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
透雲生物簽訂人民幣10億元萊茵衣藻系列產品採購協議 ACN Newswire

透雲生物簽訂人民幣10億元萊茵衣藻系列產品採購協議

香港, 2025年10月30日 - (亞太商訊 via SeaPRwire.com) - 專注於中國健康飲食行業的透雲生物科技集團有限公司(「透雲生物」,連同其附屬公司統稱「集團」;股份代號:1332.HK)欣然宣佈,集團旗下全資子公司山西透雲生物科技有限公司近日與中國健康產品領域知名渠道商多家核心夥伴,包括深圳樓宇間供應鏈科技股份有限公司、河南國字頭營銷管理有限公司及北京合萬家生物科技有限公司,組成之銷售聯合體正式簽署戰略合作協議。根據戰略合作協議,2026年至2028年底,上述銷售聯合體將向透雲生物採購總金額不少於人民幣10億元之萊茵衣藻系列產品。此標誌性合作不僅為集團萊茵衣藻業務奠定量級放大之商業基礎,亦宣示相關產品線已由區域性試點階段邁向全國化、結構化鋪排與放量,進一步夯實透雲生物於中國健康膳食、功能營養與綠色食品原料賽道的產業領先地位。本次採購協議的正式落地,標誌著透雲生物的萊茵衣藻及微藻產品已由研發驗證與先導試用階段,全面邁入可規模交付的商業化新階段 — 即具備工業化、標準化、可持續、可追溯之穩定供應能力。是次協議屬量級採購安排,亦即對產能、品質一致性、合規體系、供應鏈韌性及交付節奏的全方位驗證。對集團而言,這不僅是一筆訂單,更是一個產業拐點 — 萊茵衣藻正由「創新食材」走向「行業標配」。此里程碑進一步鞏固集團「新一代綠色蛋白與功能營養供應商」之市場定位。透雲生物不再只是提供單一原料,而是輸出一整套可複製的營養解決方案 — 涵蓋低GI配方、高蛋白/全胺基酸譜設計、富微量元素強化方案、以及針對不同消費人群(控糖人群、體重管理人群、三高風險人群、銀髮族等)的功能型膳食應用模組。集團預期,是次合作將在放量、場景擴展與C端滲透三個層面產生牽引效應:i) 推動其萊茵衣藻業務由區域性試點銷售走向全國性鋪排,實現生產端與銷售端的同步擴容與規模經濟;ii) 加速微藻原料進入更多日常高頻品類,包括健康主食、便利即食、功能代餐、餐飲定制菜單、營養加強型小食等,使其從「創新亮點」變為「常規標配」;及iii) 以B端(餐飲、渠道、大健康企業)作為推進樞紐,帶動消費端對藻基營養的認知與接受度,構建「微藻=健康」的普遍心智,為品牌後續直接面向消費者的零售型產品鋪墊基礎。集團相信,隨著是次協議所對應的採購需求逐步兌現,透雲生物將能為健康主食、控糖控脂膳食方案、功能型即食/速食產品、代餐營養品等快速增長的細分市場,提供可持續、可標準化、可長期追溯的高規格原料底座,從而在中國「健康膳食產業升級」的進程中佔據更具戰略性的供應端主導位置。透雲生物董事會主席兼執行董事王亮先生表示:「當前,消費者對健康飲食的理解已不再局限於傳統的『少油少鹽』,而是進一步聚焦於『高營養、可持續、具功能訴求』。本次簽訂人民幣10億元的戰略採購協議,乃市場對透雲生物於工業化量產能力、品質一致性、標準化交付能力以及研發迭代速度的系統性肯定。展望未來,集團將繼續強化供應鏈韌性,在保障食品安全與品質穩定的前提下,有序擴大產能,進一步完善原料端、配方端、應用端的全鏈條能力。集團會持續輸出標準化、模組化、低GI及富微量元素的整體營養解決方案,協助合作夥伴升級其核心產品線,並推動萊茵衣藻走入更廣泛的民生場景,最終讓高營養、低碳足跡的綠色食品真正普及到千家萬戶。透雲生物的戰略定位,是成為中國健康主食與功能餐飲領域的養生原料標準制定者與長期供應者,並以中國為起點,逐步走向全球。」關於透雲生物科技集團有限公司透雲生物科技集團有限公司(股份代號:1332.HK)主要從事萊茵衣藻產品業務、包裝產品設計、研發、生產及銷售業務,同時亦為向中國快速消費品提供產品包裝上的二維碼以及商務智慧資訊技術解決方案的市場領導者。集團紮根傳統包裝業務超過三十載,在香港以及廣東多地設有辦公室及製造車間,目前為眾多世界知名品牌提供專業包裝設計及製造服務,擁有長期穩定的客戶群。自2020年起,集團多元化發展業務範圍至萊茵衣藻、微藻產品業務,並與山西省長治市潞城區人民政府合作建設全球首座萊茵衣藻工廠,以展開萊茵衣藻工業化量產。如欲查詢更多資料,請瀏覽集團網站:https://touyunbiotech.com.hk/zh-hant/ Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
Northeast Asia Video Summit Spotlights Global Content Strategies, Streaming Innovation, and the Future of Media Monetization ACN Newswire

Northeast Asia Video Summit Spotlights Global Content Strategies, Streaming Innovation, and the Future of Media Monetization

TOKYO, Japan – October 30, 2025 - (ACN Newswire via SeaPRwire.com) - The Northeast Asia Video Summit 2025, hosted by the Asia Video Industry Association (AVIA), brought together leading media executives, content creators, and technology innovators to explore the future of video in Japan and Korea. Held in Tokyo, the summit showcased transformative strategies in global content production, streaming monetization, and cross-border collaboration.A central theme of the summit was the global ascent of Japanese and Korean content. In a compelling keynote, Katsuaki Setoguchi, Executive Officer at TBS Holdings and President and CEO of THE SEVEN Inc., emphasized that Japan’s ambition to go global is rooted not in profit, but in cultural promotion. “Storytelling is our foundation,” Setoguchi said, highlighting the success of Alice in Borderland and upcoming co-productions with U-Next. He outlined a formula for global success: strategic IP selection, elevated production budgets, and partnerships with platforms like Netflix and Amazon to reach a global audience. Setoguchi also stressed the importance of long-term regional collaboration, particularly in Southeast Asia, citing their strategic alliance with Vietnam TV.Yu Sasamoto, CEO of DAZN Japan and APAC Business Development, shared insights into Japan’s evolving sports streaming landscape. With partnerships like Docomo and Meta, DAZN is redefining how fans engage with live sports. Sasamoto revealed that DAZN is set to triple its subscriber base in Japan and is leveraging social media to convert engagement into subscriptions. Sasamoto also shared his ambitions to expand Japanese sports globally by building an ecosystem that blends content, technology, and partnerships to scale across Asia.Streaming monetization was another hot topic. Joshua Sunghyun Cho, CBO of TVING, detailed the platform’s innovative ad strategies, including impression-guaranteed products and interactive formats like “Watch Together.” Partnering with Moloco, TVING doubled its ad revenue from KBO baseball broadcasts and is now targeting contextual and shopping ads. “Streaming is no longer just premium branding—it’s performance-driven,” Cho said. Nick Chuah, Managing Director APAC at INVIDI, added that addressable advertising is poised to reshape Japan’s TV ad market, with data-driven campaigns delivering measurable ROI and unlocking new value for brands.Executives from Dentsu, FAST Corporation, and Integral Ad Science also echoed the need for collaboration, standardization, and advocacy to accelerate CTV adoption in Japan. With new smart TVs and platforms like TVer and ABEMA entering the programmatic space, the market is poised for rapid growth.The summit also addressed the future of anime as a global cultural force. Yuichiro Saito, CEO of Studio CHIZU, and Hideki Henry Goto, President of OKUTAGON LLC, discussed anime’s expanding international footprint. With over half of revenue now coming from global markets, speakers called for new business models, international co-productions, and talent development to sustain growth, with Saito advocating for creative integrity and global collaboration.In the closing keynote, executives from Warner Bros. Discovery, SKY Perfect JSAT, and A+E Global Media debated the future of pay TV and streaming economics in Japan. While acknowledging the slow decline of linear TV, they emphasized the enduring value of local partnerships and bundling strategies. Japan’s rich history and vibrant culture continue to produce compelling stories, presenting vast opportunities for international partnerships to bring this content to global audiences. The speakers agreed that creative distribution models and co-productions will be key to unlocking Japan’s full potential on the global stage.The Northeast Asia Video Summit is proudly sponsored by Gold Sponsors Moloco and Publica by IAS, and Silver Sponsors Encompass, INVIDI and TV5MONDE.Click here for a selection of photos from the Summit.About the Asia Video Industry AssociationThe Asia Video Industry Association (AVIA) is the trade association for the video industry and ecosystem in Asia Pacific. It serves to make the video industry stronger and healthier through promoting the common interests of its members. AVIA is the interlocutor for the industry with governments across the region, leads the fight against video piracy through its Coalition Against Piracy (CAP) and provides insight into the video industry through reports and conferences aimed to support a vibrant video industry.For media enquiries and additional background information, please contact:Charmaine KwanHead of Marketing and CommunicationsEmail: charmaine@avia.org | Website: www.avia.orgLinkedIn: www.linkedin.com/company/asiavideoia |X: @AsiaVideoIA Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
Reclaims Global Positions for Next Phase of Growth with Successful Placement and Strong Sector Momentum ACN Newswire

Reclaims Global Positions for Next Phase of Growth with Successful Placement and Strong Sector Momentum

Placement of 20,000,000 Placement Shares at S$0.39 each has been fully taken up, raising gross proceeds of S$7.8 million.Prominent institutional funds and investors that subscribed for the Placement Shares include Lion Global Investors Limited (as investment manager for and on behalf of its clients), Asdew Acquisitions Pte Ltd, ICH Synergrowth Fund, Ginko-AGT Global Growth Fund and Mr Tan Kim Seng, among others.Supported by Singapore’s robust construction outlook of S$39 billion to S$46 billion annually from 2026 to 2029 and large-scale coastal protection initiatives of S$100 billion, the Group is well-positioned to capitalise on growth opportunities with its integrated and synergistic business model.SAC Capital Private Limited acted as the Placement Agent in relation to the Placement. Maybank Securities Pte. Ltd. acted as the Placement Agent and the Sub-Placement Agent.Singapore, Oct 29, 2025 - (ACN Newswire via SeaPRwire.com) - SGX-Catalist listed Reclaims Global Limited (“Reclaims Global” or the “Company” and together with its subsidiary, the “Group”), an eco-friendly integrated service provider within Singapore’s construction sector, is pleased to announce that the Company has successfully completed a share placement (“Placement”), comprising a total of 20,000,000 new shares issued at a price of S$0.39 per share, raising gross proceeds of S$7.8 million.With its integrated and synergistic business model within Singapore’s construction industry, the Group specialises in the customisation of excavation/demolition/building construction solutions, operating fleet management of construction vehicles and equipment as well as the recycling of construction and demolition waste.“This successful placement marks a key milestone for the Group as the macro growth momentum in Singapore’s construction industry, coupled with national investment in coastal protection initiatives, creates opportunities for Reclaims Global to deliver enhanced long-term value to our stakeholders,” said Mr. Chan Chew Leh, Executive Chairman.“Building on our established foundation and track record within the construction industry, Reclaims Global is well-positioned to pursue larger-scale projects as a trusted partner. Backed by strong sectoral tailwinds, we aim to expand our market presence and capture new business opportunities via our integrated and synergistic business model,” added Mr. Tan Kok Huat, Executive Director and Chief Executive Officer.In its latest 1H2026 results (for the financial year ended 31 July 2025) announced on 9 September 2025, Reclaims Global reported revenue growth of 14.9% to S$21.78 million (as compared to previous corresponding period) with net profit of S$2.5 million. The Company has announced an interim dividend of S$0.005 per share for 1H2026 and over the past two years, the Company has paid at least S$0.01 per share of dividends annually.About Reclaims Global Limited(SGX - NEX / Bloomberg - RGL: SP/ Reuters - RECL.SI)Listed on the Catalist of the SGX-ST in March 2019, Reclaims Global Limited is an eco-friendly integrated service provider within Singapore’s construction industry, specialising in the customisation of excavation/demolition/building construction solutions, operating fleet management of construction vehicles and equipment as well as the recycling of construction and demolition waste.The Group’s integrated and synergistic business model is organised into three main business segments as follows: (1) excavation services; (2) logistics and leasing; and (3) recycling.Since its inception in 2009, the Group has established a strong reputation and proven track record for reliable execution and timely delivery of diverse projects across the construction sector.For more information, please refer to the corporate website https://reclaims-enterprise.comIssued on behalf of Reclaims Global Limited by 8PR Asia Pte Ltd.Media & Investor Contacts:Mr. Alex TANMobile: +65 9451 5252Email: alex.tan@8prasia.com Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
賽力斯開啟招股 旗下問界品牌被譽為「中國的特斯拉」 ACN Newswire

賽力斯開啟招股 旗下問界品牌被譽為「中國的特斯拉」

香港, 2025年10月30日 - (亞太商訊 via SeaPRwire.com) - 10月27日,中國新能源汽車行業中的頭部企業——賽力斯集團股份有限公司(「賽力斯」,股份代號:9927)正式啟動招股,赴港上市更進一步,此次上市若順利完成,公司有望成為港股市場首家實現「A+H」兩地上市的豪華新能源車企。問界M9豐富產品矩陣 市場表現亮眼作為一家以新能源汽車為核心業務的技術科技型企業,賽力斯業務版圖全面覆蓋新能源汽車及核心三電等產品的研發、製造、銷售及服務。公司旗下高端品牌「問界」精准聚焦豪華細分市場,憑藉清晰的產品定位、出色的綜合性能及豪華的屬性,在行業內收穫高度認可,被業內人士譽為「中國的奔馳寶馬」。而從科技維度出發,問界在品牌「智慧重塑豪華」理念的推動下,展現出「豪華+科技」雙軌並行的獨特定位。在定義未來科技出行方面,如輔助駕駛、智能安全、智能動力等,问界又與特斯拉秉持高度一致的願景。截至目前,問界系列車型的輔助駕駛功能累計行駛里程已突破34.5億公里,輔助駕駛行駛里程占總里程比例40%,輔助駕駛功能成績亮眼。與此同時,賽力斯在科技創新與前沿科技持續探索,積極佈局具身智能領域,近期公司已正式宣佈與火山引擎達成合作,共同推進具身智能的研發與應用創新,顯示出與國際領先車企不謀而合的戰略前瞻性。在科技領域的成績與探索也使得問界品牌被業內人士譽為「中國的特斯拉」。揆諸實際,無論是問界在豪華細分市場的深耕與精准定位,還是當下輔助駕駛等科技成果的穩健落地,正是對「智慧重塑豪華」品牌理念的深度踐行。這一理念精准契合用戶對智慧與豪華並重的核心訴求,讓用戶無需在豪華質感與智能體驗間作出取捨,既避免了在單一維度發展的局限,更讓「豪華 + 科技」的雙重價值真正轉化為用戶可感知的日常使用體驗。在產品端,問界品牌已構建起覆蓋問界M9、問界M8、問界M7、問界M5的完整產品矩陣,實現對高端市場的全面滲透,市場表現持續亮眼,旗下主力車型長期領跑細分市場,2024年問界M9穩居50萬級高端SUV銷量冠軍,問界M8在2025年4月正式上市後僅24小時大定即突破3萬。根據Frost & Sullivan報告,問界品牌在2024年下半年以82%的NPS淨推薦值登頂新能源汽車口碑榜首,且2024年問界品牌全年總交付量達38.71萬輛,同比增長268%,充分印證了其在高端新能源汽車市場的核心競爭力。問界全系列強化研發投入與技術創新 業績增長強勁在夯實產品矩陣、鞏固市場份額的同時,賽力斯持續深耕技術創新領域,以高強度研發投入築牢發展根基。於2022年、2023年、2024年以及2025年上半年,公司研發開支分別達人民幣1,313.7百萬元、人民幣1,696.5百萬元、人民幣5,585.5百萬元及人民幣2,929.5百萬元,呈現顯著增長態勢。從研發費用占收入比重來看,各期分別為3.9%、4.7%、3.8%及4.7%,彰顯出公司對技術創新的高度重視。領先的核心技術能力,是賽力斯的產品持續實現功能創新、獲得市場成功的重要驅動力之一。公司自主打造的魔方技術平臺,通過平臺化造車模式,有效降低了整車開發成本,同時大幅提升開發的敏捷性和靈活性。該平臺憑藉全景安全、多元動力、百變空間、智慧引領四大核心優勢,為用戶提供了「好開、好用、超安全」的智能用車體驗。同時,作為首家商業化量產增程器的自主整車企業,賽力斯持續引領新能源車增程技術的發展,將增程技術從「可用」進化到「好用」,並在油電轉換率和NVH性能兩項關鍵指標上獲得國家權威認證機構的認可,其最新發佈的全新一代超級增程系統油電轉換效率達到3.65kWh/L,處於行業量產增程器的最高水平。此外,賽力斯始終將產品安全視為底線,圍繞車輛全生命週期,構建了涵蓋被動安全、主動安全等九大維度的智能安全體系。目前,公司開發了81項碰撞場景,搭載該體系的問界M9榮獲C-NCAP、C-IASI國內兩大測評指數雙第一的優異成績。在ESG治理與可持續發展領域中,賽力斯也取得亮眼成績,2025年10月16日,根據國際權威指數公司明晟(MSCI) 公佈最新企業ESG評級結果,賽力斯集團獲得最高AAA評級,成為唯一獲此評級的A股上市汽車企業,彰顯賽力斯集團在構建未來出行生態中的引領力量。值得一提的是,公司通過融合創新的方式與合作夥伴共同打造了先進的智能座艙和輔助駕駛功能,並通過深度融合整車控制技術,從整車跨域協同維度持續優化輔助駕駛體驗,為用戶提供更加智能、便捷的駕駛感受。財務表現上,賽力斯近年業績增長勢頭強勁,盈利成果顯著。2023年至2024年,公司收入從人民幣358億元躍升至1451億元,同比大幅增長305.5%;公司毛利率同步提升,從2023年的7.2%穩步增至2025年上半年的26.5%,盈利空間持續拓寬。盈利層面,公司於2024年、2025年上半年分別錄得歸母淨利潤人民幣59億元、人民幣29億元,成功實現盈利突破。根據Frost & Sullivan報告,公司是全球第四家實現盈利的新能源車企,財務健康度與行業競爭力凸顯。總體而言,賽力斯憑藉清晰的高端產品佈局、領先的技術創新與穩健的盈利增長,已在新能源汽車賽道建立起穩固的行業地位。此次擬赴港上市,既是對其過往發展成果的認可,更將為其深化技術研發、拓展全球市場注入新動能,有望在全球汽車產業變革中持續領跑,為中國自主品牌車企高質量發展寫下新的注腳。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
產品與技術共築堅固護城河「中國的特斯拉」賽力斯招股進行時 ACN Newswire

產品與技術共築堅固護城河「中國的特斯拉」賽力斯招股進行時

香港, 2025年10月30日 - (亞太商訊 via SeaPRwire.com) - 10月27日,中國新能源汽車行業頭部企業—賽力斯(股份代號:9927)啟動招股,目前招股正在進行中,即將叩開港股市場大門,有望成為首家A+H豪華新能源車企。極具競爭力的產品體系在產品層面,賽力斯憑藉深厚的技術積澱與精准的市場定位,構建起極具競爭力的產品體系。其中,公司於2021年重磅發佈的高端品牌「問界」,截至目前,問界品牌已成功推出問界M5、問界M7、問界M8及問界M9四款核心產品,累計服務用戶已突破80萬。更值得關注的是,公司旗下主力車型長期穩居細分市場頭部陣營,問界M9持續領跑高端SUV賽道,穩居50萬級市場銷量冠軍。問界M8始終穩居40萬級市場榜首,成為高端用戶的首選之一。問界M9憑藉「雙旗艦」車型的亮眼表現與強大品牌影響力,賽力斯被業界高度認可,贏得了「中國的奔馳寶馬」這一重磅讚譽,彰顯出公司在高端新能源汽車市場的領軍地位。在定義輔助駕駛、智能安全、智能動力等未來出行領域,賽力斯與特斯拉秉持高度一致的願景。截至目前,問界系列車型的輔助駕駛功能累計行駛里程已突破34.5億公里,在該領域,僅特斯拉與問界穩居前兩位,疊加賽力斯在具身智能與科技創新領域的持續深耕與積極探索,赛力斯被行業廣泛視作「中國的特斯拉」。問界對豪華市場的深耕定位與輔助駕駛等科技成果的落地,既是 “智慧重塑豪華” 理念的深度實踐,也精准匹配用戶對智慧與豪華兼具的需求,跳出單一維度發展局限,讓 “豪華 + 科技” 價值成為用戶可感知的體驗。全方位的技術創新實力在技術層面,賽力斯持續推動技術創新,逐步確立行業競爭優勢並打造堅實的技術壁壘。公司自主研發的魔方技術平台,是具備持續進化能力的智能平台,也是行業內首個兼容增程、純電與混動三種新能源動力總成的平台,其模塊化設計使公司能夠高效、可靠地實現系列車型的快速量產。目前,賽力斯最新一代超級增程系統已實現量產,熱效率高達44.8%,油電轉化率達到3.65kWh/L,處於行業領先水平。 魔方技術平台在用戶安全方面,賽力斯以全場景安全需求為驅動,全面構建覆蓋被動安全、主動安全等九大維度的安全體系,涵蓋超過180項用戶用車場景,開發出300余項安全功能,打造全方位的安全防護能力。此外,賽力斯還構建了端雲一體化的測試平台,其自研的智能測試終端可實現測試車輛7×24小時不間斷的自動化測試。通過自動化測試技術,公司構建了覆蓋研發、生產、供應、銷售全流程的質量自動化攔截體系,全面保障產品質量。賽力斯在 ESG 治理與可持續發展領域同樣成效顯著,2025 年 10 月 16 日拿下國際權威機構明晟(MSCI)最高 AAA 評級,作為 A 股上市車企中唯一獲此評級的企業,其未來出行生態引領地位得以凸顯。財務方面,賽力斯近年來實現跨越式增長,業績表現尤為亮眼。2024年營業收入突破1451億元,同比增長305.5%,實現歸母淨利潤59億元,成功實現歷史性扭虧為盈,2025年上半年,公司延續盈利向好態勢,實現淨利潤29億元,展現出強勁增長勢頭。賽力斯以產品力、技術壁壘與安全體系築牢發展根基,憑亮眼財務數據印證強勁實力。若此次赴港上市順利落地,其將正式開啟「A+H」雙資本平台驅動模式,未來有望持續領跑高端新能源賽道,書寫行業發展新篇章。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
賽力斯赴港招股:問界「智慧重塑豪華」引領新能源趨勢 ACN Newswire

賽力斯赴港招股:問界「智慧重塑豪華」引領新能源趨勢

香港, 2025年10月30日 - (亞太商訊 via SeaPRwire.com) - 汽車產業邁向電動化、智能化轉型的關鍵時刻,中國品牌正加速崛起。賽力斯集團股份有限公司(下稱「賽力斯」,股份代號:9927)於10月27日正式開啟港股招股,有望成為首家實現A+H兩地上市的豪華新能源汽車企業。此次IPO,賽力斯計劃全球發售100,200,000股股份,最高發售價為每股131.50港元,預計募集資金淨額約129.249億港元,並定於11月5日正式登陸香港聯合交易所。此次上市由中金公司與中國銀河國際擔任聯席保薦人。賽力斯旗下高端品牌「問界」(AITO)憑藉其系列車型,已在30萬元至50萬元級別的細分市場中領跑,被業界譽為「中國的Mercedes Benz寶馬」。問界以「智慧重塑豪華」為核心理念,不僅契合用戶對智能科技與豪華駕乘的雙重追求,同時也因其在輔助駕駛、智能安全及智能動力等方面的技術成果,被視為「中國的特斯拉」,展現出與全球頂尖智能電動車製造商一致的願景。技術積澱與華為深度合作賽力斯的成功並非偶然,其背後是超過三十年的技術積澱。公司自1986年創立以來,深耕汽車製造領域,從傳統燃油車的紮實製造基礎,平穩過渡至新能源汽車的創新浪潮。2021年,問界品牌的發佈標誌著賽力斯正式錨定豪華新能源汽車賽道,並確立了「用戶定義汽車」的市場導向與「軟件定義汽車」的技術路線,迅速構築起差異化的競爭優勢。問界目前已形成M5、M7、M8、M9四大主力產品矩陣,通過精準的價格梯度與場景化功能組合,全面搶佔高端用戶市場。問界系列車型亦受益於與華為的深度合作,而華為作為智能汽車系統的領軍者,為問界提供了強大的智能駕駛和智能座艙技術支持,使其在輔助駕駛的體驗和智能化水平上,持續保持行業領先地位,這也是問界系列能夠獲得市場認可的關鍵要素。問界M9領跑高端市場問界品牌的強勁表現已在銷售數據上得到充分印證。2024年,問界全年交付量達到38.71萬輛,同比實現268%的爆炸性增長。在細分市場中,旗艦車型問界M9上市僅10個月內生產逾15萬輛,一舉拿下50萬元級別的銷量冠軍寶座,展現出強大的品牌力和市場號召力。為保障產品質量與交付效率,賽力斯投入巨資建設「超級工廠」並優化數字化供應鏈體系,有力支撐了產品「上市即上量」的策略。在實現垂直上量交付的同時,問界M9系列在垂直上量交付中至今未出現任何重大質量問題,為業界樹立了高質量交付的新標桿。賽力斯此次赴港上市,不僅是其發展歷程中的重要里程碑,更將為國際投資者提供一個深度參與中國豪華智能電動車市場高速增長的絕佳機會。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
OTS Holdings Celebrates the Grand Opening of its New Manufacturing Facility, Ellaziq (Malaysia) Sdn. Bhd., in Johor, Malaysia; Marks Major Expansion in its Halal Production Capacity ACN Newswire

OTS Holdings Celebrates the Grand Opening of its New Manufacturing Facility, Ellaziq (Malaysia) Sdn. Bhd., in Johor, Malaysia; Marks Major Expansion in its Halal Production Capacity

SINGAPORE, Oct 29, 2025 - (ACN Newswire via SeaPRwire.com) - OTS Holdings Limited (“OTS Holdings” or the “Company”, and together with its subsidiaries, the “Group”), a brand builder and food manufacturing group, is pleased to announce the grand opening of its new advanced food manufacturing facility located at Lot 1734, Jalan Kampung Pisang, Bukit Keremoiyang, 86200 Simpang Renggam, Johor Darul Takzim, Malaysia. The facility will operate under a wholly-owned subsidiary Ellaziq (Malaysia) Sdn. Bhd.The event on 28 October 2025 was graced by Yang Berhormat Tuan Lee Ting Han, Chairman of the Johor State Investment, Trade, Consumer Affairs and Human Resources Committee, along with representatives from the Malaysian Investment Development Authority (MIDA), Enterprise Singapore, the Singapore Business Federation, the Johor State Islamic Religious Department, as well as representatives from banking institutions, partners, and business associates.From left to right: 1. Mr. Mohamad Reduan Mohd Zabri, Director, MIDA Johor; 2. Ms. Wan Hariati Wan Salleh, Senior Deputy Director, Food Technology & Resources Based Industries Division, MIDA; 3. Yang Berhormat Tuan Lee Ting Han, Chairman of Johor State Investment, Trade, Consumer Affairs and Human Resources Committee; 4. Mr. Ong Bee Chip, Managing Director, OTS Holdings Limited; 5. Mdm. Ong Chew Yong, Executive Director, OTS Holdings Limited; and 6. Dr. Yu Lai Boon, Non-Executive Chairman and Independent Director, OTS Holdings LimitedWith a total investment of approximately RM40 million, the new Johor manufacturing facility is halal certified and equipped with new advanced F&B machinery and automation, boosting the Group’s monthly halal production capacity by up to 200 tonnes — more than three times of its Singapore’s halal production output.Backed by advanced production capabilities and in-house R&D expertise, the Group has undertaken extensive renovation and upgrading works, since acquiring the property for RM14.3 million in November 2023, to ensure the new facility aligns with the Group’s stringent food manufacturing standards, quality controls and operational requirements.With a land size of 178,863 square feet, the Johor manufacturing facility has a built-up area of 65,000 square feet that includes office space, production and maintenance facility with boilerhouse and workshop.Dedicated exclusively to halal production, the Johor manufacturing facility has successfully obtained its halal certification in August 2025.Notably, the Johor manufacturing facility is equipped with new advanced F&B machinery and automation, which will enable the Group to maintain stringent quality standards while operating with a lean workforce.In comparison to the Singapore facility, which produces 60 tonnes of halal products monthly within 17,000 square feet, the Johor plant will boast a capacity of up to 200 tonnes per month — more than three times of Singapore’s production output.Commenting on the grand opening of its new Johor manufacturing facility, Managing Director of OTS Holdings, Mr. Ong Bee Chip said: “Our new Johor facility reflects our commitment to meeting the evolving needs of the Muslim consumer segment, which continues to grow both in value and demand.Our focus is not just on increasing volume, but on creating products that resonate with the values and expectations of the Muslim community, while maintaining the stringent standards of food quality and safety.Targeting the growing Muslim consumer market locally and abroad—from Singapore and Malaysia to the Middle East, UAE, and Africa, our enhanced production capacity will also strengthen our export capabilities, extending our trusted halal brands and high quality products to a larger audience globally.”About OTS Holdings Limited(Bloomberg: OTS:SP / SGX Stock Code: OTS)Established in 1993, OTS Holdings Limited is a brand builder and food manufacturing group in the consumer industry with a strong niche in ready-to-eat and ready-to-cook meat products with key markets in Singapore and Malaysia.The Group’s vision is to develop a growing portfolio of established consumer brands and become an innovative market leader in the region. Targeting both halal and non-halal consumer segments, the Group has more than 1,100 SKUs across 13 main product types under its eight house brands and notably the Group’s flagship brands, “Golden Bridge” and “Kelly’s” have become established household names within the ready-to-eat and ready-to-cook meat products market in Singapore and Malaysia.The Group owns and operates three modern food manufacturing facilities, two in Singapore and one in Simpang Renggam, Johor, Malaysia. In Singapore, its integrated food manufacturing facilities with in-house research and development team span across around 98,285 square feet with an average annual production of around 2,500 tonnes of ready-to-eat and ready-to-cook meat products.The Group’s food products are sold in major supermarkets, convenience stores, provision shops, hotels and restaurants in Singapore and Malaysia. Having built an established sales and distribution network over the past few decades, the Group aims to expand its presence in existing markets and overseas.For more information, please visit the Company’s website at www.ots-holdings.com.Issued on behalf of OTS Holdings Limited by 8PR Asia Pte Ltd.Media & Investor Contacts:Mr. Alex TANMobile: +65 9451 5252Email: alex.tan@8prasia.com Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
國泰君安國際助力滴普科技成功登陸港交所主板 ACN Newswire

國泰君安國際助力滴普科技成功登陸港交所主板

香港, 2025年10月29日 - (亞太商訊 via SeaPRwire.com) - 2025年10月28日,國泰海通集團下屬公司國泰君安國際控股有限公司(「國泰君安國際」,股票代碼:1788.HK)作爲聯席保薦人、整體協調人、保薦人兼整體協調人、聯席全球協調人、聯席帳簿管理人及聯席牽頭經辦人,助力中國領先的企業級大模型人工智能應用解决方案提供商滴普科技股份有限公司(「滴普科技」,股票代碼:1384.HK)于10月28日在香港聯交所主板成功上市。滴普科技本次港股成功上市,是國泰海通集團充分整合境內外資源的又一典範之作。在本項目中,國泰君安國際充分發揮其溝通協調與執行能力,開展了精准高效的路演推介與深入的投資者溝通,成功助力本次IPO成爲中國企業級大模型人工智能應用解决方案領域募資規模領先的港股項目,進一步鞏固了滴普科技在企業級大模型人工智能解决方案市場的競爭優勢。本次項目的成功執行,彰顯了國泰君安國際在港股IPO市場,尤其是服務新經濟及特專科技企業方面的領先地位。本次發行最終定價爲每股26.66港元,總發售股數達2,663.2萬股,總集資額約爲7.1億港元。香港公開發售錄得踴躍認購,認購倍數約爲7,569倍,顯示出市場對滴普科技在企業級人工智能解决方案領域領先地位及未來增長潜力的高度認可。公司計劃將募集資金用于以下戰略方向:約40%用于提升研發能力;約30%用于擴大在中國的銷售網絡及客戶群;約15%用于海外業務擴張;約5%用于潜在投資及幷購;10%將作爲營運資金及一般公司用途。此資金規劃將爲滴普科技鞏固技術壁壘和加速商業化進程提供堅實動力。早在2021年,國泰君安國際聯合領投滴普科技1億美金B輪融資,2022年認繳完畢,充分展現了公司前瞻性地布局人工智能賽道、精准把握高成長企業潜力的戰略眼光,也爲後續助力滴普科技登陸港股市場奠定了堅實的合作基礎。未來,國泰君安國際將繼續憑藉其專業的金融服務能力,致力于爲更多創新科技企業連接全球資本市場。關于滴普科技滴普科技是中國領先的企業級大模型人工智能應用解决方案提供商,通過其FastData企業級數據智能解决方案和FastAGI企業級人工智能解决方案助力企業大規模高效整合數據、决策及運營。以2024年收入計,滴普科技在中國企業級大模型人工智能應用解决方案市場排名第五。其解决方案已實現多個垂直行業的規模商業化落地,覆蓋消費零售、製造、醫療及交通等領域。截至2025年6月30日,滴普科技爲各行業累計283名企業用戶提供服務,複購客戶占比33.2%,體現了高度的客戶粘性及客戶滿意度。關于國泰君安國際國泰海通集團下屬公司國泰君安國際(股票代號:1788.HK),是中國證券公司國際化的先行者和引領者,公司是首家通過IPO于香港聯合交易所主板上市的中資證券公司。國泰君安國際以香港爲業務基地,幷在新加坡、越南和澳門設立子公司,業務覆蓋全球主要市場,爲客戶境外資産配置提供高品質、多元化的綜合性金融服務,核心業務包括財富管理、機構投資者服務、企業融資服務、投資管理等。目前,國泰君安國際已分別獲得穆迪和標準普爾授予「Baa2」及「BBB+」長期發行人評級,MSCI ESG「A」評級, Wind ESG「A」評級及商道融綠ESG「A」評級,同時其標普全球ESG評分領先全球84%同業。公司控股股東國泰海通證券(股票代號:601211.SH/2611.HK)爲中國資本市場長期、持續、全面領先的綜合金融服務商。更多關于國泰君安國際的資訊請見:https://www.gtjai.com Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
Ecological Threat Report 2025: Extreme Wet-Dry Seasons Emerge as Critical Conflict Catalyst ACN Newswire

Ecological Threat Report 2025: Extreme Wet-Dry Seasons Emerge as Critical Conflict Catalyst

LONDON, Oct 29, 2025 - (ACN Newswire via SeaPRwire.com) - New research from the Institute for Economics & Peace reveals that changing rainfall patterns are significantly amplifying conflict risks worldwide. The 2025 Ecological Threat Report (ETR), released today, finds conflict death rates are substantially higher in areas where rainfall is concentrating into fewer months, compared to regions where rain is spreading more evenly throughout the year.Ecological Threat Report 2025Analysing Ecological Threats, Resilience & PeaceKey FindingsOn average in areas where wet and dry seasons are becoming more extreme, there are four times as many conflict deaths as areas where it has decreased.In 2024, natural hazards triggered 45 million short-term internal displacements across 163 countries, the highest figure since at least 2008.Western Brazil, including parts of the Amazon, has recorded some of the world's sharpest increases in ecological threat levels. Temperatures have risen at twice the global rate, triggering drought and wildfires.Sub-Saharan Africa faces the world's most severe ecological pressures, with Niger registering the worst ETR score.Central and Western Europe recorded substantial overall improvements, in part representing a return to normalcy following Europe's unusually dry climatic conditions in 2019.Despite fears of looming water wars, there have been no interstate conflicts fought exclusively over water in the modern era. In the second half of the 20th century, at least 157 international freshwater treaties have been signed, offering models for interstate cooperation.This cooperative approach to water somewhat mirrors nuclear deterrence since the Second World War. In both cases, the very threat of catastrophic destruction has created pragmatic cooperation. The destruction of water supply can lead to societal collapse.Approximately 2 billion people - one quarter of humanity - now live in regions experiencing moderate to severe increases in seasonality. This is where wet seasons are becoming shorter and more intense, while dry seasons are longer and drier. These changes are disrupting agricultural calendars and heightening uncertainty for billions of people who rely on seasonal rains for food and livelihoods.The Ecological Threat Report, produced by the Institute for Economics & Peace, covers 3,125 sub-national areas in 172 countries and territories representing more than 99% of the world's population. Between 2019 and 2024, ETR scores deteriorated in 96 countries and improved in 74.Sub-Saharan Africa Approaching Multiple Critical Tipping PointsIn sub-Saharan Africa, conflict risk rises sharply when seasonality combines with rapid population growth. Unpredictable rains trigger agricultural stress. When coupled with demographic pressure, competition over land, water and food intensifies. In regions with weak governance and unresolved grievances, this combination proves combustible.The Karamoja Cluster in East Africa illustrates this pattern. While total rainfall remains relatively stable, its timing has become less predictable, amplifying both drought and flood hazards, leading to increased conflict. With only 2% of cultivated land irrigated compared to a global average of 20%, East African communities remain highly vulnerable to these shocks. Since 2019, increased rainfall seasonality has coincided with a resurgence of pastoralist violence after years of relative peace."Rainfall seasonality is becoming a powerful conflict catalyst,"said Steve Killelea AM, Founder & Executive Chairman of the Institute for Economics & Peace."Where rains are increasingly concentrated into fewer months, conflict deaths rise sharply. In sub-Saharan Africa, rapid population growth amplifies this effect, turning unpredictable seasons into competition for land, water and food. The issue isn't water scarcity - it's our failure to capture and distribute it. Only 2% of Sub-Saharan African farmland is irrigated, compared to 20% globally."Water Inequality and the Infrastructure GapThe world's renewable freshwater supply is finite and increasingly unevenly distributed. There are 295 subnational areas facing very high water risk and another 780 with high risk, affecting nearly 1.9 billion people.High-income countries have reduced per capita water use by roughly one-third since 2000 through efficiency gains and slower population growth, while many low-income nations face rising total withdrawals and falling per capita availability as populations outpace supply.Sub-Saharan Africa highlights this imbalance. Per capita water use has dropped from 113 cubic metres in 2000 to just 89 in 2022 - less than one-fifth of the global average. The result is mounting pressure on limited water sources and intensifying competition among farms, industries and households, heightening the risk of conflict.The failure to capture and distribute water is most acute in sub-Saharan Africa, which has the lowest irrigation rates in the world. To irrigate 34 million hectares would require only 6% of the region's annual renewable water resources.Steve Killelea said: "COP30 must prioritise investment in climate-resilient water systems as a foundation for sustainability and peace. Just as nuclear treaties reduced the risk of annihilation, international cooperation on water can reduce the risk of ecological collapse. Both demonstrate that survival depends less on dominance, than on shared responsibility."Interstate Water CooperationPopular narratives have warned of looming "water wars", especially in transboundary river and lake basins. The ETR finds this is not the case. While disputes over shared rivers do occur, no interstate wars have been fought over water in the modern era. This makes the lessons of successful interstate water cooperation even more important. In an era of increasing conflict, understanding why interstate cooperation has been so successful can provide a blueprint for avoiding future conflicts.Even in tense basins such as the Indus River - shared by India and Pakistan - water-sharing has continued despite repeated episodes of conflict, political confrontations and military tension. Water agreements, by necessity, encourage nations to think beyond immediate political grievances toward long-term survival and shared benefit.Regional AnalysisSub-Saharan Africa faces the world's most severe ecological pressures. However, some southern and eastern African countries, including Lesotho, Rwanda, Eritrea and Eswatini, have improved their ETR scores. More favourable rainfall patterns in these countries resulted in marked reductions in water risk over the past five years.In contrast, northwest Africa has seen the steepest deterioration in ETR scores over the same period, led by Tunisia, Morocco and Algeria, where persistent drought and rising temperatures have reversed the unusually favourable conditions of 2019.Central and Western Europe recorded notable improvements, marking a return to normal following the extreme dryness of 2019.Contact InformationMike KoslowskiIEP Senior Communications Advisormkoslowski@economicsandpeace.org+61418410531SOURCE: Institute for Economics & PeaceRelated Images Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
GTJAI Assisted Deepexi Technology in Successfully Listing on the Main Board of the Hong Kong Stock Exchange ACN Newswire

GTJAI Assisted Deepexi Technology in Successfully Listing on the Main Board of the Hong Kong Stock Exchange

HONG KONG, Oct 29, 2025 - (ACN Newswire via SeaPRwire.com) – October 28, As the joint sponsor, overall coordinator, sponsor-overall coordinator, joint global coordinator, joint bookrunner and joint lead manager, Guotai Junan International Holdings Limited (“GTJAI”, stock code: 1788.HK), a company of Guotai Haitong Group, facilitated the successful listing of Deepexi Technology Co., Ltd. (“Deepexi Technology”, stock code: 1384.HK), a leading enterprise large model AI application solution provider in China, on the main board of the Hong Kong Stock Exchange on October 28.The successful listing of Deepexi Technology exemplifies Guotai Haitong Group’s strength in integrating domestic and international resources. In this project, GTJAI fully leveraged its communication, coordination and execution capabilities to conduct precise and efficient roadshows and in-depth investor engagement. This successfully positioned the IPO as the leading Hong Kong-listed project in terms of fundraising scale of China's enterprise large model AI application solution sector, further solidifying Deepexi Technology’s competitive edge in the enterprise large model AI application solution market. The successful execution of this project underscores GTJAI’s leading position in the Hong Kong IPO market, particularly in serving new economy and specialized technology enterprises.The final offering price of this issuance is set at HK$26.66 per share, with a total of 26.632 million shares offered. The total funds raised amount to approximately HK$710 million. The Hong Kong public offering recorded an overwhelming subscription, with an oversubscription ratio of approximately 7,569 times, demonstrating the market's strong recognition of Deepexi Technology’s leading position in the enterprise large model AI application solution sector and its future growth potential. The company plans to allocate the raised funds to the following strategic directions: approximately 40% for enhancing R&D capabilities; approximately 30% for expansion of sales network and customer base in China; approximately 15% for overseas business expansion; approximately 5% for potential investment, mergers and acquisitions; and 10% for working capital and general corporate purposes. This funding plan will provide solid momentum for Deepexi Technology to consolidate its technological barriers and accelerate its commercialization process.Notably, as early as 2021, GTJAI co-led a USD$100 million Series B financing round for Deepexi Technology , which was completed in 2022. This early involvement demonstrated GTJAI’s strategic foresight in identifying high-growth potential in the AI sector and laid a solid foundation for subsequent collaboration in supporting Deepexi Technology’s listing in Hong Kong. In the future, GTJAI will continue to leverage its professional financial services capabilities to connect more innovative technology companies with global capital markets. About Deepexi TechnologyDeepexi Technology is China's leading provider of enterprise large model AI application solutions. Through its FastData enterprise data intelligence solution and FastAGI enterprise AI solution, it empowers enterprises to integrate their data, decisions and operations efficiently at scale. Deepexi Technology ranked fifth in China’s enterprise large model AI application solution market in terms of revenue in 2024. Its solutions have achieved large-scale commercialization across multiple verticals, including consumer goods, manufacturing, healthcare and transportation. As of June 30, 2025, Deepexi Technology served a cumulative total of 283 enterprise customers across various industries, with multiple engagements representing 33.2% of customer base, reflecting strong customer loyalty and satisfaction. About GTJAIGuotai Junan International (Stock Code: 1788.HK), a subsidiary of Guotai Haitong Group, is the market leader and first mover for internationalization of Chinese Securities Company as well as the first Chinese securities broker listed on the Main Board of The Hong Kong Stock Exchange through initial public offering. Based in Hong Kong with subsidiaries in Singapore, Vietnam and Macau, GTJAI’s business covers major markets around the world, offering high-quality and diversified comprehensive financial services for clients' overseas asset allocation. Core business includes wealth management, institutional investor services, corporate finance services, investment management and other business. GTJAI has been assigned “Baa2” and “BBB+” long term issuer rating from Moody and Standard & Poor respectively, as well as an MSCI ESG “A” rating, Wind ESG “A” rating and SynTao Green Finance “A” rating in ESG. Additionally, its S&P Global ESG score leads 84% of its global peers. The controlling shareholder, Guotai Haitong Securities (Stock Code: 601211.SH/ 2611.HK), is the comprehensive financial provider with a long-term, sustainable and overall leading position in the China’s capital markets. For more information about GTJAI, please visit https://www.gtjai.com. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
國泰君安國際獨家保薦劍橋科技 成就A股H股通信設備行業最大規模IPO ACN Newswire

國泰君安國際獨家保薦劍橋科技 成就A股H股通信設備行業最大規模IPO

香港, 2025年10月29日 - (亞太商訊 via SeaPRwire.com) - 2025年10月28日,國泰海通集團下屬公司國泰君安國際控股有限公司(「國泰君安國際」或「公司」,股份代號:1788.HK)作爲獨家保薦人、保薦人兼整體協調人、整體協調人、聯席全球協調人、聯席賬薄管理人及聯席牽頭經辦人,成功助力上海劍橋科技股份有限公司(「劍橋科技」,股份代號:6166. HK,603083.SH)在香港聯交所主板上市。劍橋科技由此成爲光模塊及CPO(Co-packagedoptics,光電共封裝技術)領域首家實現「A+H」雙平臺上市的企業。此次港股發行創下A股與港股通信設備行業有史以來最大規模IPO紀錄,充分彰顯國泰海通集團在跨境資本運作中高效整合資源、服務大型科技企業的綜合實力。本次發行最終定價爲每股68.88港元,總發售股數達6,701萬股,基礎發行規模46.16億港元,超額配售權完全行使後預計總集資額將達53.08億港元。國際配售和香港公開發售錄得踴躍認購,國際配售認購倍數達16.5倍,香港公開發售認購倍數達338.7倍。截至2025年10月28日,以募資規模計,本項目爲2025年前三大獨家保薦港股IPO項目。在項目執行過程中,國泰君安國際憑藉高效的溝通協調與執行力,助力劍橋科技在六個月內完成從遞交H股上市申請到成功在港挂牌的全流程。項目團隊深入挖掘和打造公司投資故事,聚焦公司在AI基礎設施、光通信及光模塊領域的領先地位及技術優勢,開展扎實深入的市場推介工作,對接全球頂尖投資者,幫助劍橋科技引入霸菱、摩根士丹利、HCEP、Arc Avenue、奇點資産、Weiss、Cithara、3W、Schonfeld、無極資本、Alpine、Dymon Asia、博裕、Martis、泰康人壽、工銀理財共計16名頂尖基石投資者,基石投資占比48.89%,涵蓋頂尖外資長綫基金、知名外資多策略基金、中資長綫基金,幷于國際配售中進一步引入衆多全球頂尖長綫基金和主權基金訂單,既展現了國泰君安國際領先的全球投資者覆蓋能力,也凸顯了全球頂尖資本對劍橋科技長期發展前景的信心。關于劍橋科技劍橋科技是全球領先的AI基礎設施提供商,專注于光模塊、寬帶和無綫等聯接與傳輸設備的設計、研發、製造與銷售,其産品廣泛應用于算力集群內部、算力集群之間、算力集群與用戶之間以及用戶端內部大量算力和數據的高效連接,下游客戶包括全球領先的人工智能數據中心、電信運營商、ICT設備提供商、多系統運營商及物聯網解决方案提供商。公司在中國、美國及日本設立了六大研發中心,通過自有工廠和Co-location合作模式,公司在中國、美國、歐盟及馬來西亞設立了七大生産基地。憑藉公司在行業內的强勢地位及廣泛的全球布局,公司將持續受益于人工智能高速發展帶來的巨大增長機遇。關于國泰君安國際國泰海通集團下屬公司國泰君安國際(股票代號:1788.HK),是中國證券公司國際化的先行者和引領者,公司是首家通過IPO于香港聯合交易所主板上市的中資證券公司。國泰君安國際以香港爲業務基地,幷在新加坡、越南和澳門設立子公司,業務覆蓋全球主要市場,爲客戶境外資産配置提供高品質、多元化的綜合性金融服務,核心業務包括財富管理、機構投資者服務、企業融資服務、投資管理等。目前,國泰君安國際已分別獲得穆迪和標準普爾授予「Baa2」及「BBB+」長期發行人評級,MSCI ESG「A」評級, Wind ESG「A」評級及商道融綠ESG「A」評級,同時其標普全球ESG評分領先全球84%同業。公司控股股東國泰海通證券(股票代號:601211.SH/2611.HK)爲中國資本市場長期、持續、全面領先的綜合金融服務商。更多關于國泰君安國際的資訊請見:https://www.gtjai.com Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
GTJAI Serves as the Sole Sponsor for CIG, Achieving the Largest IPO in the Telecommunications Equipment Sector across Both A-shares and H-shares Markets ACN Newswire

GTJAI Serves as the Sole Sponsor for CIG, Achieving the Largest IPO in the Telecommunications Equipment Sector across Both A-shares and H-shares Markets

HONG KONG, Oct 29, 2025 - (ACN Newswire via SeaPRwire.com) – October 28, As the sole sponsor, sponsor-overall coordinator, overall coordinator, joint global coordinator, joint bookrunner and joint lead manager, Guotai Junan International Holdings Limited (“GTJAI” or “the Company”, stock code: 1788.HK), a company of Guotai Haitong Group, facilitated the successful listing of CIG SHANGHAI CO., LTD. (“CIG”, stock code: 6166.HK,603083.SH) on the main board of the Hong Kong Stock Exchange. This listing establishes CIG as the first photonics and CPO (Co-packaged Optics) company with dual listings in both the A-share and H-share markets. Marking the largest IPO ever in the telecommunications equipment sector across these markets, the offering fully demonstrates Guotai Haitong Group's comprehensive capabilities in resource integration and serving large technology enterprises through cross-border capital operations. The final offering price for this issuance is set at HK$68.88 per share, with a total of 67.01 million shares offered, representing a base offering size of HK$4.616 billion. Upon full exercise of the over-allotment option, the total proceeds are expected to reach HK$5.308 billion. The offering attracted strong investor interest, with the international placement oversubscribed by approximately 16.5 times and the Hong Kong public offering oversubscribed by approximately 338.7 times. As of October 28, 2025, this transaction ranks among the top three Hong Kong IPO projects by fundraising size led by a sole sponsor in 2025. Throughout the project execution, GTJAI leveraged its efficient communication, coordination and execution capabilities to assist CIG in completing the entire process—from submitting its H-share listing application to successfully listing in Hong Kong—within six months.The project team conducted in-depth research and crafted the company's investment narrative, highlighting its leading position and technological advantages in AI infrastructure, optical communication and photonics. Through robust and thorough market outreach, they connected with the world's top investors and assisted CIG in engaging a total of 16 top-tier cornerstone investors, including Barings, Morgan Stanley, HCEP, Arc Avenue, CloudAlpha Capital, Weiss, Cithara, 3W, Schonfeld, Infini Capital, Alpine, Dymon Asia, Boyu, Martis, Taikang Life and ICBC WM with cornerstone investments accounting for 48.89% of the total. These investors encompass premier foreign long-term funds, renowned foreign multi-strategy funds and Chinese long-term funds. International placement further secured orders from numerous top global long-term funds and sovereign wealth funds. This achievement not only demonstrates GTJAI’s leading global investor coverage capabilities but also underscores the confidence of world-class capital in CIG’s long-term development prospects. About CIGCIG is a globally leading AI infrastructure provider specializing in the design, R&D, manufacturing and sales of connectivity and transmission equipment such as photonics, broadband and wireless solutions. Its products are extensively deployed for efficient connectivity within computing clusters, between clusters, between clusters and users, and within user endpoints to manage massive computing power and data flows. Its downstream clients include world-leading AI data centres, telecom operators, ICT equipment providers, multiple system operators and internet-of-things solutions providers. The company has established six major R&D centres in China, the United States and Japan. Through its own manufacturing facilities and Co-location partnerships, it has set up seven production bases in China, the United States, the European Union and Malaysia. Leveraging its strong industry position and extensive global footprint, the company will continue to benefit from the tremendous growth opportunities presented by the rapid advancement of artificial intelligence.About GTJAIGuotai Junan International (Stock Code: 1788.HK), a subsidiary of Guotai Haitong Group, is the market leader and first mover for internationalization of Chinese Securities Company as well as the first Chinese securities broker listed on the Main Board of The Hong Kong Stock Exchange through initial public offering. Based in Hong Kong with subsidiaries in Singapore, Vietnam and Macau, GTJAI’s business covers major markets around the world, offering high-quality and diversified comprehensive financial services for clients' overseas asset allocation. Core business includes wealth management, institutional investor services, corporate finance services, investment management and other business. GTJAI has been assigned “Baa2” and “BBB+” long term issuer rating from Moody and Standard & Poor respectively, as well as an MSCI ESG “A” rating, Wind ESG “A” rating and SynTao Green Finance “A” rating in ESG. Additionally, its S&P Global ESG score leads 84% of its global peers. The controlling shareholder, Guotai Haitong Securities (Stock Code: 601211.SH/ 2611.HK), is the comprehensive financial provider with a long-term, sustainable and overall leading position in the China’s capital markets. For more information about GTJAI, please visit https://www.gtjai.com Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
第20屆國際環保博覽今天揭幕 ACN Newswire

第20屆國際環保博覽今天揭幕

- 第20屆國際環保博覽今天起一連四天於亞洲國際博覽館舉行,吸引來自13個國家及地區、約340家展商參與- 博覽多元活動和產品科技響應施政報告,涵蓋循環經濟及廢物處理、綠色及智慧出行、以及ESG相關服務三大領域- 大會將於明天舉行「環保企業"走出去" 經驗交流會」,多位一帶一路國家政府官員及半官方機構代表分享開拓當地市場策略,助環保企業拓闊國際網絡香港, 2025年10月28日 - (亞太商訊 via SeaPRwire.com) - 由香港貿易發展局(香港貿發局)、法蘭克福展覽(香港)有限公司合辦,並由香港特別行政區政府環境及生態局協辦的第20屆國際環保博覽,今日起一連四天(10月28至31日)於亞洲國際博覽館舉行,吸引來自13個國家及地區、約340家展商,帶來各式創新環保科技產品、ESG及可持續發展方案,為業界打造優質的商貿平台。博覽最後一天(即10月31日)為公眾日,免費開放予公眾人士入場,鼓勵市民參與環保活動,實踐綠色生活。中華人民共和國生態環境部副部長于會文、工業和信息化部節能與綜合利用司副司長丁志軍、香港特別行政區環境及生態局局長謝展寰、香港貿發局總裁張淑芬、法蘭克福展覽(香港)有限公司執行董事李慶新等,今日出席國際環保博覽開幕典禮。香港貿發局總裁張淑芬表示:「今年國際環保博覽迎來第20屆的重要里程碑,不僅展示我們對可持續發展的承諾,也凸顯我們持續推動綠色創新及與綠色業界合作生態圈的使命。今年博覽以『綠色科技 引領零碳未來』為主題,為綠色產業提供寶貴的交流機會,再次匯聚業界領袖共同為永續的未來鋪路,這亦與香港特區政府的淨零排放目標互相配合。」環境及生態局局長謝展寰於開幕典禮致辭時表示:「在全球邁向可持續發展的過程中,香港發揮『超級聯繫人』的角色。憑藉我們作為粵港澳大灣區內國際都會的獨特地位,以及擔當中國內地對接世界的橋樑,香港匯聚人才、科技與資本,能促進合作和擴大綠色創新。」環球展商雲集 展示創新環保科技今年博覽共有17個展團,本地方面,環境運動委員會首次組織展館,帶來22家本地綠色初創,還有環境及生態局等11個政府單位組成的展區等。中國內地包括廣東、廣州、深圳、廣西、湖南、上海、內蒙古亦組團參展。由『一帶一路』國際科學組織聯盟(ANSO)及11家內地企業組成的ANSO環境科技產業聯盟展館更首次亮相,展示與水資源和大氣環境有關的技術,藉著參展為聯盟企業開拓海外市場奠定基礎。海外展團方面,今年新增韓國及意大利展團,挪威、荷蘭及加拿大展團亦載譽歸來。大會積極建構平台協助港商及內地企業「出海」,吸引來自日本、泰國、印尼、馬來西亞、新加坡、越南、匈牙利及波蘭的買家組團參觀及採購。至於明天舉行的「環保企業"走出去"經驗交流會」,特區政府邀請多位一帶一路國家政府官員及半官方機構代表分享開拓當地市場策略。大會亦與環境及生態局合作,廣邀內地、東盟及「一帶一路」國家政府的服務供應商,親臨博覽採購環保科技及產品。三大領域響應施政報告 智能與環保兼具環保成為近年政策焦點之一,中國內地近期發布《關於推進綠色低碳轉型加強全國碳市場建設的意見》,成為指引「十五五」時期中國碳市場深化改革的綱領性文件。今年政府亦提出建設綠色低碳生活環境,致力加速綠色技術應用等。配合產業發展,博覽匯聚多元綠色科技,展示循環經濟及廢物處理、綠色及智慧出行、以及ESG相關服務三大領域最新成果。在循環經濟及廢物處理展區,綠色人工智能科技(展位編號:3-D38)展示AI 智能分類垃圾桶,裝置可透過即時AI廢物識別,提供互動學習體驗,教授正確回收方法。另外,綠色動力環保集團(展位編號:3-E30)帶來再生能源發電廠項目,助力城市永續發展。於綠色及智慧出行領域,內地裝備制造業龍頭三一集團港澳地區子公司三一騰飛機械(展位編號:6-C26)則帶來三一鋰能電源車,可同時為兩台電動卡車充電。 內地潔淨能源設備製造商中集安瑞科控股有限公司(展位編號:3-F14),展示用於運輸和儲存氫能及綠色甲醇的創新技術方案。博覽亦帶來ESG相關服務,Llewellyn and Partners Company(展位編號:6-D14)帶來為建築業而設的專利AI 綜合管理平台AutoTwin,協助減少建築運營成本、時間及碳排放。加拿大科技公司XSIM AI Canada Inc.(展位編號:6-C23)則透過AI驅動的系統,為污水處理廠及工業設施減少高達30%的停機時間、營運成本及碳排放。學研機構與初創亦不容忽視,除香港中文大學(展位編號:3-G24)亦再度參與外,嶺南大學(展位編號:6-A25)和香港理工大學晉江技術創新研究院(展位編號:6-A23)今年首次參展。香港科技園公司(展位編號:3-F20)帶來初創afterNATURE(展位編號:3-F20),展出六角形深水盆,用以維持海岸線的生態與海洋生物多樣性而設。另一家園區初創遠見築(展位編號:3-F20)則展示AtmosBrick 及於博覽全球首發AtmosTile「負碳」綠建材,將二氧化碳轉化為高性能建材,大幅降低碳足跡。業界領袖聚首「亞洲環保會議」建造業與交通運輸業成焦點博覽焦點活動「亞洲環保會議」今天舉行政府環節,中華人民共和國工業和信息化部節能與綜合利用司副司長丁志軍在會上分享國家最新環保政策及動向,緬甸、斯里蘭卡、菲律賓等多個一帶一路國家的政府官員亦會講解當地最新綠色政策及項目;同日另一環節則以「循環經濟:革新與創新解決方案」為主題,由商界環保協會帶領多位專家,探討如何在商業運營上應用循環經濟概念,會議中亦會首度推出《香港循環建築環境指南》,為建造業帶來最新綠色指引。博覽第三日(10月30日)的會議主題圍繞「構建可持續未來:邁向淨零建築環境」及「綠色智慧出行 - 引領未來出行潮流」,邀請多位業界領袖及專家分享真知灼見,包括機電工程署副署長陳柏祥、香港生產力促進局先進能源及智慧交通中心技術及商品化主管莫天德博士等,分別討論建築業及交通運輸行業如何透過有效合作,構建可持續發展城市。其他精彩活動包括博覽首日(10月28日)的「香港工業總會.Q嘜低碳餐廳大獎」頒獎典禮;於第二日(10月29日)舉行的第六屆氫能經濟論壇,香港特區政府環境及生態局副局長黄淑嫻屆時會帶來主題演講,而中國城市燃氣氫能發展創新聯盟副理事長王子緣將分享粵港澳大灣區氫能機遇與挑戰。博覽同時設有不同研討會,包括為推動綠色初創企業發展而設的「初創.動起來」,邀請來自不同環保領域的初創代表進行分享。博覽於最後一天(10月31日)為公眾日,免費開放予市民入場,鼓勵市民參與環保活動。當日特設一系列的環保生活講座、工作坊和活動,當中包括近期熱話極端天氣,由香港天文台總學術主任陳敏儀進行分享;海洋公園亦會分享「逆瀕行動 Mission R」保護瀕危野生動物與其棲息環境的相關資訊。市民亦可參與不同環保工作坊,同場亦設有綠色市集供市民選購環保產品。其他同期活動香港國際戶外及科技照明博覽在10月28至31日同於亞博館舉行,展示各種商業和工業用的室外及專業技術照明解決方案,而香港國際秋季燈飾展(秋燈展)已於昨天起一連四天(10月27日至30日)在香港會議展覽中心舉行。大會已安排免費穿梭巴士服務,往來展場及各主要酒店與交通交匯點。詳情請參閱以下網頁︰https://www.hktdc.com/event/ecoexpoasia/tc/travel-to-fairground-awe圖片下載:https://bit.ly/48MjH8F由香港貿發局及法蘭克福展覽(香港)有限公司合辦的第20屆國際環保博覽揭幕,博覽一連四天(10月28至31日)假亞洲國際博覽館舉行,吸引約340家展商參與。圖為中華人民共和國生態環境部副部長于會文、工業和信息化部節能與綜合利用司副司長丁志軍、香港特別行政區環境及生態局局長謝展寰、香港貿發局總裁張淑芬及一眾嘉賓,出席國際環保博覽開幕典禮盛況。中華人民共和國生態環境部副部長于會文(左三)、香港特別行政區環境及生態局局長謝展寰(右三)、香港貿發局總裁張淑芬(左二)及一眾嘉賓到場參觀。香港特區政府邀請多位一帶一路國家及地區的政府官員及半官方機構代表出席第20屆國際環保博覽,包括柬埔寨、緬甸及斯里蘭卡等。今年博覽共有17個展團參展,當中包括環境運動委員會首次組織展館,帶來22家本地初創。海外展團方面,今年新增韓國展團,陣容鼎盛。綠色及智慧出行屬今年新增領域,聚焦於各種嶄新的綠色運輸方案及產品。業界新血亦不容忽視,學研機構與初創帶來創新綠色方案。「亞洲環保會議」邀請來自世界各地的官員、行業領袖和專家,就不同議題分享真知灼見。網頁國際環保博覽:www.ecoexpoasia.com/tc傳媒查詢請聯絡香港貿發局傳訊及公共事務部:蘇顯博電話:(852) 2584 4049電郵:stanley.hp.so@hktdc.org劉茸電話:(852) 2584 4472電郵:clayton.y.lauw@hktdc.org香港貿發局新聞中心︰http://mediaroom.hktdc.com/tc香港貿易發展局簡介香港貿易發展局(香港貿發局)是於1966年成立的法定機構,負責促進、協助和發展香港貿易。香港貿發局在世界各地設有超過50個辦事處,其中13個設於中國內地,致力推廣本港作為雙向環球投資及商業樞紐。 香港貿發局通過舉辦國際展覽會、會議及商貿考察團,為企業(尤其是中小企業)開拓內地和環球市場的機遇。香港貿發局亦通過研究報告和數碼資訊平台,提供最新的市場分析和產品資訊。有關香港貿發局的其他資訊,請瀏覽www.hktdc.com/aboutus/tc。法蘭克福展覽集團簡介法蘭克福展覽集團是全球最大的擁有自主展覽場地的展會主辦機構之一,其業務覆蓋展覽會、會議及活動,在全球29個地區聘用約2,160名員工,業務版圖遍及世界各地。2022年營業額約4.54億歐元,集團與眾多行業領域建立了豐富的全球商貿網絡並保持緊密聯繫,在展覽活動、場地和服務業務領域,高效滿足客戶的商業利益和全方位需求。法蘭克福展覽集團核心優勢在於遍布世界各地龐大、緊密的國際行銷網絡,覆蓋全球約180個國家。多元化的服務呈現在活動現場及網絡平台的各個環節,確保遍布世界各地的客戶在策劃、組織及進行活動時,能持續享受到高品質及靈活性。我們正在通過新的商業模式積極拓展數字化服務範疇,可提供的服務類型包括租用展覽場地、展會搭建、市場推廣、人力安排以及餐飲供應。作為核心戰略體系之一,集團積極實踐可持續化經營理念,在生態、經濟利益、社會責任和多樣性之間達成有益的平衡。有關集團可持續發展進一步資料,請瀏覽網頁:www.messefrankfurt.com/sustainability。集團總部位於德國法蘭克福市,由該市和黑森州政府分別控股60%和40%。有關公司進一步資料,請瀏覽網頁:www.messefrankfurt.com.hk。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
OctoHorizon: Where Engineering Shapes the Future of Trading ACN Newswire

OctoHorizon: Where Engineering Shapes the Future of Trading

GEORGE TOWN, KY, Oct 28, 2025 - (ACN Newswire via SeaPRwire.com) - Octo Horizon, a proprietary trading firm specializing in high-frequency trading (HFT), is advancing the next generation of trading infrastructure - where engineering excellence, low-latency systems, and high-performance software drive measurable results.octo-horizon-high-performance-infrastructureEngineering-driven infrastructure at Octo Horizon powers next-generation trading technology.The firm approaches trading as a large-scale engineering challenge, focusing on optimizing system performance, network throughput, and execution speed. Engineers at Octo Horizon work on cutting-edge infrastructure using C++, concurrency design, and deterministic architectures to ensure reliable, predictable operation under demanding conditions. Kernel-bypass networking, lock-free data structures, and real-time analytics are among the tools applied to reduce latency and maximize efficiency.Engineering at the CoreEngineering precision is central to Octo Horizon's philosophy. Teams collaborate on high-performance software, distributed systems, and real-time data processing, tuning every layer - from network drivers to execution logic - to achieve optimal performance. Continuous benchmarking, profiling, and performance analysis are embedded in the development workflow to maintain stable, predictable results.Developers also engage in rigorous testing frameworks, including unit, integration, and stress testing, to validate system reliability under peak load conditions. Tooling for monitoring, logging, and performance visualization is integrated into the workflow, allowing engineers to identify bottlenecks and optimize system throughput at the nanosecond scale.Technology PhilosophyFor Octo Horizon, trading is a technical pursuit. The firm emphasizes simplicity, reproducibility, and system-level optimization, solving complex problems in low-latency networking, asynchronous processing, and event-driven architectures. Teams design modular, maintainable systems that scale efficiently and adapt to evolving market conditions, while minimizing resource overhead.Real-time decision-making and deterministic behavior are central, with every system component evaluated for latency, concurrency, and stability. This approach ensures that the firm's technology remains reliable, resilient, and capable of supporting high-throughput electronic markets.Culture and CollaborationOcto Horizon fosters a collaborative and innovation-driven environment. Engineers, systems developers, and quantitative researchers work closely across disciplines to exchange ideas, review designs, and refine implementations. Autonomy, technical curiosity, and attention to detail are highly valued, creating a culture where individual expertise drives measurable impact and continuous improvement.Opportunities for Engineers and ResearchersOcto Horizon is expanding its technology and research teams and is actively hiring for the following positions:Quantitative ResearcherSoftware EngineerDevOps EngineerCandidates passionate about high-performance computing, distributed systems, and low-latency software are encouraged to apply. The firm offers an environment that rewards technical mastery, curiosity, and innovation - with the opportunity to work on challenging real-world problems with visible results.For more information and to apply, visit https://www.octo-horizon.com/jobsContact InformationMedia Octo Horizonservice@octo-horizon.comSOURCE: Octo Horizon Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
OctoHorizon:以工程塑造交易的未來 ACN Newswire

OctoHorizon:以工程塑造交易的未來

喬治敦,肯塔基, 2025年10月28日 - (亞太商訊 via SeaPRwire.com) - 作為一家專注於高頻交易(HFT)的自營交易公司,Octo Horizon 正在推動下一代交易基礎設施的發展——在這裡,卓越的工程能力、低延遲系統和高性能軟件共同驅動可衡量的成果。octo-horizon-high-performance-infrastructure該公司將交易視為一項大型工程挑戰,專注於優化系統性能、網絡吞吐量和執行速度。Octo Horizon 的工程師們致力於使用 C++、並發設計和確定性架構開發最前沿的基礎設施,以確保在高要求的環境下實現可靠、可預測的運行。內核旁路網絡、無鎖數據結構以及實時分析等技術工具被廣泛應用於降低延遲、提升效率。工程為核心工程精確性是 Octo Horizon 核心理念的基礎。團隊在高性能軟件、分佈式系統和實時數據處理領域密切合作,對每一層——從網絡驅動到執行邏輯——進行精細調校,以實現最佳性能。持續的基準測試、性能分析和剖析被嵌入開發流程中,以確保系統結果穩定且可預測。開發人員還參與嚴格的測試體系,包括單元測試、整合測試和壓力測試,以驗證系統在高負載條件下的可靠性。監控、日誌記錄和性能可視化等工具被整合進工作流程,使工程師能夠在納秒級別識別瓶頸並優化系統吞吐量。技術理念對 Octo Horizon 來說,交易是一項技術性的探索。公司強調簡潔性、可重現性和系統級優化,致力於解決低延遲網絡、異步處理以及事件驅動架構中的複雜問題。團隊設計模組化、可維護的系統,使其能夠高效擴展並適應不斷變化的市場環境,同時儘量減少資源開銷。實時決策與確定性行為是核心原則。每個系統組件都會從延遲、並發性和穩定性等維度進行評估。這種方法確保公司技術體系的可靠性、韌性,以及支持高吞吐量電子化市場的能力。文化與協作Octo Horizon 致力於營造協作與創新並重的工作環境。工程師、系統開發人員和量化研究員跨學科緊密合作,交流思想、審查設計並優化實現。公司高度重視自主性、技術好奇心和細節專注度,形成一種以個人專業能力驅動可衡量成果與持續改進的文化。工程師與研究員的機遇Octo Horizon 正在擴大其技術與研究團隊,現正積極招聘以下職位:量化研究員軟件工程師DevOps 工程師我們誠邀熱衷於高性能計算、分佈式系統和低延遲軟件開發的優秀人才加入。公司提供一個鼓勵技術精進、探索精神與創新思維的環境,讓您有機會參與解決具有挑戰性的實際問題,並見證切實成果。欲了解更多信息並申請,請訪問 https://www.octo-horizon.com/jobs 聯絡信息Media Octo Horizonservice@octo-horizon.com來源: Octo Horizon Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
GMG Achieves Major Commercial Milestone – THERMAL-XR(R) to be Distributed Through Australian Beijer Ref and Kirby Network ACN Newswire

GMG Achieves Major Commercial Milestone – THERMAL-XR(R) to be Distributed Through Australian Beijer Ref and Kirby Network

Brisbane, Australia--(ACN Newswire via SeaPRwire.com - October 28, 2025) - Graphene Manufacturing Group Ltd. (TSXV: GMG) (OTCQX: GMGMF) ("GMG" or the "Company") is pleased to announce that Beijer Ref has agreed to offer the Company's proprietary THERMAL-XR® ENHANCE heat transfer coating as an optional coating solution on Beijer Ref and Kirby branded refrigeration evaporator coils, including the Beijer Patton and Kirby Guardian lines as seen in Figure 1, across all of Beijer Ref's and Kirby's approximately 73 wholesale locations in Australia starting from 17 November 2025. Beijer Ref customers electing to have the optional coating solution applied to their Beijer Ref or Kirby refrigeration evaporator coils will contract directly with Beijer Ref, who will enter into a bilateral agreement with the Company, subject to GMG's standard terms and conditions. This collaboration marks a significant milestone in GMG's commercialization of its innovative coating products for energy efficiency and corrosion resistance in the HVAC-R industry.Figure 1: Beijer Patton Evaporator Coil and Kirby Guardian Evaporator CoilTo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/272201_gmg_figure1_550.jpgWhile the collaboration is for an indeterminate period, the Company anticipates that as the advantages of THERMAL-XR® ENHANCE are experienced by customers electing to have the coating applied, the benefits to both Beijer Ref and the Company will support a long-term arrangement. However, at present either party may terminate the collaboration at any time.Beijer Ref is one of the world's largest global refrigeration and HVAC wholesalers, headquartered in Malmö, Sweden, with operations spanning more than 40 countries and over 500 branches worldwide, 6,000 employees and 200,000 customers. In Australia, Beijer Ref Group distributes through Kirby, Beijer Ref Australia, SCM REF Australia, and ACD Trade, providing air conditioning and refrigeration equipment, components, and engineering solutions. The company serves diverse sectors such as supermarkets, cold storage, and industrial refrigeration, combining expertise with local manufacturing and distribution capabilities.GMG's THERMAL-XR® ENHANCE coating utilizes the Company's unique graphene-based formulation to improve the thermal performance and longevity of heat exchange surfaces. The application of this coating to Beijer Patton and Kirby Guardian evaporator coils is expected to enhance corrosion resistance, cooling efficiency, reduce energy consumption and provide sustainability benefits across diverse cooling environments. This initiative extends the availability of GMG's product through Beijer Ref's extensive distribution network while offering Australian customers improved system performance and energy/emission reduction pathways.GMG plans to utilize a network of trained and approved HVAC contractors to apply its THERMAL-XR® ENHANCE coating on refrigeration and air-conditioning coils for this roll out for coating Beijer Ref products starting in the capital cities of mainland Australia. Each participating contractor will undergo GMG certification in the GMG SPRAY ACADEMY to ensure they are proficient in the coating's three-stage process: surface cleaning and preparation, graphene-based coating application, and post-application inspection and maintenance verification. This ensures consistent quality, adherence to safety protocols, and correct use of GMG's proprietary application methods.These certified contractors will deliver coating services on-site or at pre-approved GMG spray coating plants nationally, enabling GMG to scale deployment seamlessly through both direct and distributor channels, particularly in collaboration with Beijer Ref and Kirby stores. By drawing on established HVAC service professionals, the Company ensures local availability, rapid turnaround for installations, and full compliance with the quality standards required for quality assurance.This contractor program forms part of GMG's strategic commercialization model, where trained technicians act as frontline partners in the installation of graphene-enhanced coatings for end users. The approach maximizes accessibility, maintains warranty integrity, and strengthens GMG's reputation for technical excellence and customer support across Australia's HVAC-R market.GMG's Chief Executive Officer, Craig Nicol, commented: "We are proud to see THERMAL-XR® ENHANCE incorporated into Beijer Ref's and Kirby's product offerings in Australia as an option for their leading HVAC-R products. This partnership demonstrates the growing recognition of graphene-enhanced materials as a viable route to corrosion resistance and greater efficiency in conventional HVAC-R systems. The Company continues to expand its market reach globally through strategic channel partners and remains committed to advancing environmentally responsible technologies through graphene innovation."GMG's Chairman and Non-Executive Director, Jack Perkowski, commented "Congrats to the team – great to see this next step in the roll out of GMG's global leading energy saving products."About GMG:GMG is an Australian based clean-technology company which develops, makes and sells energy saving and energy storage solutions, enabled by graphene manufactured via in house production process. GMG uses its own proprietary production process to decompose natural gas (i.e. methane) into its natural elements, carbon (as graphene), hydrogen and some residual hydrocarbon gases. This process produces high quality, low cost, scalable, 'tuneable' and low/no contaminant graphene suitable for use in clean-technology and other applications.The Company's present focus is to de-risk and develop commercial scale-up capabilities, and secure market applications. In the energy savings segment, GMG has initially focused on graphene enhanced heating, ventilation and air conditioning ("HVAC-R") coating (or energy-saving coating) which is now being marketed into other applications including electronic heat sinks, industrial process plants and data centres. Another product GMG has developed is the graphene lubricant additive focused on saving liquid fuels initially for diesel engines.In the energy storage segment, GMG and the University of Queensland are working collaboratively with financial support from the Australian Government to progress R&D and commercialization of graphene aluminium-ion batteries ("G+AI Batteries"). GMG has also developed a graphene additive slurry that is aimed to improve the performance of lithium-ion batteries.GMG's 4 critical business objectives are:Produce Graphene and improve/scale cell production processesBuild Revenue from Energy Savings ProductsDevelop Next-Generation BatteryDevelop Supply Chain, Partners & Project Execution CapabilityFor further information please contact:Craig Nicol, Chief Executive Officer & Managing Director of the Company at craig.nicol@graphenemg.com, +61 415 445 223Leo Karabelas at Focus Communications Investor Relations, leo@fcir.ca, +1 647 689 6041Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accept responsibility for the adequacy or accuracy of this news release.Cautionary Note Regarding Forward-Looking Statements This news release includes certain statements and information that may constitute forward-looking information within the meaning of applicable Canadian securities laws. Forward-looking statements relate to future events or future performance and reflect the expectations or beliefs of management of the Company regarding future events. Generally, forward-looking statements and information can be identified by the use of forward-looking terminology such as "intends", "expects" or "anticipates", or variations of such words and phrases or statements that certain actions, events or results "may", "could", "should", "would" or will "potentially" or "likely" occur. This information and these statements, referred to herein as "forward‐looking statements", are not historical facts, are made as of the date of this news release and include without limitation, statements regarding the offering of THERMAL-XR® ENHANCE heat transfer coating on Beijer Ref and Kirby branded refrigeration evaporator coils, THERMAL-XR® ENHANCE's ability to enhance corrosion resistance, cooling efficiency, reduce energy consumption, and provide sustainability benefits across diverse cooling environments, improve system performance and energy/emission reduction pathways, the intention to utilize a network of trained and approved HVAC contractors to apply its THERMAL-XR® ENHANCE coating, the proficiency of contractors in the application of THERMAL-XR® ENHANCE, the delivery of coating services on-site or at pre-approved GMG spray coating plants, the Company's ability to scale deployment seamlessly, the Company's ability to ensure local availability, rapid turnaround for installations, and full compliance with the quality standards required for quality assurance, the strategic commercialization model's ability to maximize accessibility, maintain warranty integrity, and strengthen GMG's reputation for technical excellence and customer support across Australia's HVAC-R market, the growth in recognition of graphene-enhanced materials as a viable route to corrosion resistance and greater efficiency in conventional HVAC-R systems, the Company's continued expansion of its market reach globally through strategic channel partners and the Company's commitment to advancing environmentally responsible technologies through graphene innovation.Such forward-looking statements are based on a number of assumptions of management, including, without limitation, that GMG will be able to take orders and deliveries to meet distributor demand around the worldwide. Additionally, forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of GMG to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation, that products may not be available for sales or delivery to meet customers' expectations.Although management of the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements and forward-looking information. Readers are cautioned that reliance on such information may not be appropriate for other purposes. The Company does not undertake to update any forward-looking statement, forward-looking information or financial out-look that are incorporated by reference herein, except in accordance with applicable securities laws. To view the source version of this press release, please visit https://www.newsfilecorp.com/release/272201 Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
The 20th Eco Expo Asia opens today ACN Newswire

The 20th Eco Expo Asia opens today

- The 20th edition of Eco Expo Asia opens today for four days at AsiaWorld-Expo, gathering some 340 exhibitors from 13 countries and regions- The Expo features diverse activities and product technologies in response to the Policy Address, covering three key areas – Circular Economy and Waste Management, Green & Smart Mobility and ESG-related Services- The ‘Experience Sharing Forum on Promoting Environmental Business in Overseas Markets’ will be held tomorrow. Government officials and representatives of quasi-governmental organisations from Belt and Road countries will share strategies for local market development, to help green companies expand their international networksHONG KONG, Oct 28, 2025 - (ACN Newswire via SeaPRwire.com) – The 20th Eco Expo Asia, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd and co-organised by the Environment and Ecology Bureau of the Government of the Hong Kong Special Administrative Region (HKSAR), opened at AsiaWorld-Expo today and runs until 31 October. Some 340 exhibitors from 13 countries and regions are showcasing innovative green technologies and products, as well as ESG and sustainable solutions. The last day of the Expo, 31 October, will open to the public for free, to encourage sustainable living practices.Yu Huiwen, Vice Minister of the Ministry of Ecology and Environment of the People’s Republic of China; Ding Zhijun, Deputy Director of the Department of Energy Conservation and Comprehensive Utilization, Ministry of Industry and Information Technology of the People’s Republic of China; Tse Chin-wan, Secretary for Environment and Ecology of the Hong Kong SAR Government; HKTDC Executive Director Sophia Chong; and Richard Li, Executive Director of Messe Frankfurt (HK) Ltd, attended Eco Expo’s opening ceremony today.HKTDC Executive Director Sophia Chong said: “This year, we celebrate a significant milestone of the Expo - its 20th edition. This not only marks our commitment to sustainability but also underscores our ongoing mission to develop the ecosystem for driving innovation and collaboration to support the green agenda. Under the theme ‘Green Innovations for Carbon Neutrality’, Eco Expo Asia provides invaluable opportunities for the green industry. This year, once again, we are bringing together leading players from the eco sector to pave the way for a more sustainable future, in alignment with the Hong Kong SAR Government’s net zero goals.”Speaking at the opening ceremony, the Secretary for Environment and Ecology, Tse Chin-wan, said, "In the global journey towards sustainability, Hong Kong serves as a ‘super connector’. With our unique position as an international city within the Guangdong-Hong Kong Macao Greater Bay Area and a bridge between Chinese Mainland and the world, Hong Kong brings together talent, technology, and capital to foster collaboration and scale up green innovation.Global exhibitors gather to showcase innovative environmental technologiesThis year’s Expo brings together 17 pavilions. For the first time, the Environmental Campaign Committee is hosting a pavilion, presenting 22 local green start-ups, alongside a joint government pavilion featuring 11 bureaux and departments, including the Environment and Ecology Bureau. Chinese Mainland delegations from Guangdong, including Guangzhou and Shenzhen, Guangxi, Hunan, Inner Mongolia and Shanghai are also joining the Expo. The ANSO Environmental Technology Industry Alliance, led by the Alliance of National and International Science Organizations for the Belt and Road Regions (ANSO), is making its debut, together with 11 mainland enterprises, showcasing technologies related to water resources and the atmospheric environment, and laying the foundation for future expansion overseas. New overseas pavilions include Italy and South Korea, while Canada, the Netherlands and Norway are returning this year.The Expo is also actively building a platform to support Hong Kong and mainland enterprises to go global and explore new opportunities in green trade, attracting buyers from Japan, Thailand, Indonesia, Malaysia, Singapore, Vietnam, Hungary and Poland to visit and source at the event. For tomorrow’s ‘Experience Sharing Forum on Promoting Environmental Business in Overseas Markets’, the Hong Kong SAR Government has invited government officials and representatives from quasi-governmental organisations from Belt and Road countries to share strategies to develop local markets. In collaboration with the Environment and Ecology Bureau, the Expo extends invitations to government service providers from the Chinese Mainland, as well as from ASEAN and Belt and Road countries, to visit and source green technologies and products.Three major green and smart areas supporting the Policy AddressEnvironmental protection has become a key policy focus in recent years. The Chinese Government recently released guidelines on advancing low-carbon transition and strengthening the development of China’s carbon trading market. This year’s Policy Address highlighted new directions in green policy in Hong Kong, including fostering green and low-carbon living environments, and expediting the application of green technologies. In line with industry development, the Expo brings together a diverse range of green tech, showcasing the latest achievements in Circular Economy and Waste Management, Green & Smart Mobility and ESG-related Services.In Circular Economy and Waste Management, Green AI Technology Limited (Booth No. 3-D38) displays its AI-powered smart sorting bin with real-time waste identification, demonstrating good recycling methods through interactive learning. Dynagreen Environmental Protection Group Co., Ltd (Booth No. 3-E30) showcases its comprehensive waste treatment project, contributing to sustainable urban development.In Green & Smart Mobility, SANY Turbo Fly Machine Limited (Booth No. 6-C26) from Hong Kong and Macao, a subsidiary of SANY Group, a leading equipment manufacturing company in the Chinese Mainland, brings its SANY Mobile Charging Power Station, which can charge two electric trucks simultaneously. CIMC Enric Investment Holding (Shenzhen) Co., Ltd. (Booth No. 3-F14), a leading manufacturer of advanced clean energy equipment, showcases innovative hydrogen and green methanol technology solutions for transportation and storage.The Expo also showcases ESG-related services. Llewellyn and Partners Company Limited (Booth No. 6-D14) displays AutoTwin, a patented AI-powered integrated management platform for the construction industry, which helps reduce building operating costs, time and carbon emissions. XSIM AI Canada Inc.,(Booth No. 6-C23), a Canadian technology company, empowers wastewater and industrial facilities with its AI-driven system to reduce downtime and lower operational costs, while cutting carbon emissions by up to 30% .Research institutions and start-ups also play a significant role in the Expo. In addition to the return of The Chinese University of Hong Kong (Booth No. 3-G24), Lingnan University (Booth No. 6-A25) and the Hong Kong Polytechnic University Jinjiang Technology and Innovation Research Institute (Booth No. 6-A23) are joining for the first time this year. The Hong Kong Science and Technology Parks Corporation (Booth No. 3-F20) presents start-up afterNATURE (Booth No. 3-F20), which is showcasing its Deep Hexagonal Basin product. This innovation creates habitats for marine life on its surface, helping to preserve coastal biodiversity. Another start-up, Formwork IO (Booth No. 3-F20), exhibits AtmosBrick and is globally debuting AtmosTile at the Expo. These ‘carbon-negative’ building materials are designed to help reduce carbon emissions.Eco Asia Conference brings together industry leaders, focusing on construction and transportation sectorsEco Expo’s highlight event, Eco Asia Conference, began today with the Government Session. Ding Zhijun, Deputy Director of the Department of Energy Conservation and Comprehensive Utilization, Ministry of Industry and Information Technology of the People’s Republic of China, shared the country’s latest environmental policies and trends. Officials from Myanmar, Sri Lanka, the Philippines and other Belt and Road countries also elaborated on their latest green policies and projects. Another session, ‘Revolutionising with Circular Economy: From Waste to Innovative Solutions’, featured experts led by the Business Environment Council, who explored the application of circular economy concepts in business operations. The Hong Kong Circular Built Environment Guidebook is also making its debut at the Conference, providing the latest green guidelines for the construction industry.On the third day of the Expo, on 30 October, the Conference will have two main themes: ‘Building a Sustainable Future: Gearing Towards a Net-Zero Built Environment’ and ‘Green & Smart Mobility – Envisioning the Future of Transportation’. Industry leaders and experts, including Pak-cheung Chan, Deputy Director, Electrical and Mechanical Services Department, Hong Kong SAR Government, and Dr Rick Mo, Head of the Centre of Advanced Power and Autonomous Systems (APAS), Hong Kong Productivity Council, will share insights and discuss how the construction and transportation industries can build sustainable cities through effective collaboration.Other exciting activities include the FHKI Q-Mark Low Carbon Restaurant Award 2025 on 28 October, the first day of the Expo. The 6th Hydrogen Economy Forum will be held on the second day of the Expo, on 29 October. Diane Wong, JP, Under Secretary for Environment and Ecology, Hong Kong SAR Government will deliver the keynote address, while Dr Wang Ziyuan, Vice President, China Hydrogen Development and Innovation Alliance for Urban Gas will share insights on the opportunities and challenges of hydrogen energy in the Guangdong-Hong Kong-Macao Greater Bay Area. The Expo also features various seminars, including ‘Startup Edge’, which promotes the development of green start-ups, featuring presentations by start-up representatives from various environmental fields.On 31 October, Eco Expo will open to the public free of charge, to encourage public participation in environmental initiatives through a series of talks, workshops and activities. These include a seminar on the recent hot topic of extreme weather by Man Yee Chan, Chief Experimental Officer, Hong Kong Observatory, and a presentation by Ocean Park on Mission R, an initiative to protect endangered wildlife and their habitats. The public can also participate in various environmental workshops, and purchase eco-friendly products from the Green Mart.Other concurrent eventsThe Hong Kong International Outdoor and Tech Light Expo takes place from 28 to 31 October at AsiaWorld-Expo, showcasing outdoor and professional technical lighting solutions for commercial and industrial use; while the Hong Kong International Lighting Fair (Autumn Edition) opened yesterday and will run until 30 October at the Hong Kong Convention and Exhibition Centre. Free shuttle bus services are offered between these venues and other locations in the city throughout the fair period. Please refer to the following page for details:https://www.hktdc.com/event/ecoexpoasia/en/travel-to-fairground-awePhoto download: https://bit.ly/48MjH8FThe 20th Eco Expo Asia, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd, opened at AsiaWorld-Expo today and runs until 31 October, attracting some 340 exhibitors. Yu Huiwen, Vice Minister of the Ministry of Ecology and Environment of the People's Republic of China, Ding Zhijun, Deputy Director of the Department of Energy Conservation and Comprehensive Utilization, Ministry of Industry and Information Technology of the People’s Republic of China; Tse Chin-wan, Secretary for Environment and Ecology of the Hong Kong SAR Government; Sophia Chong, HKTDC Executive Director, and other honourable guests attended the opening ceremonyYu Huiwen, Vice Minister of the Ministry of Ecology and Environment of the People's Republic of China (third left), Tse Chin-wan, Secretary for Environment and Ecology of the Hong Kong SAR Government (third right), Sophia Chong, HKTDC Executive Director (second left), and other honourable guests visited the ExpoThe Hong Kong SAR Government has invited government officials and representatives of quasi-governmental organisations from Belt and Road countries and regions, including Cambodia, Myanmar and Sri Lanka, to attend the 20th Eco Expo AsiaThis year’s Expo brings together 17 pavilions. For the first time, the Environmental Campaign Committee is hosting a pavilion, presenting 22 local green start-upsKorea is a new pavilion from overseas, with a strong lineupGreen and Smart Mobility is a new zone that has been added this year, focusing on green transport solutions and productsIndustry newcomers, such as research institutions and start-ups, bring innovative green solutionsThe Eco Asia Conference gathers global officials, industry leaders and experts to exchange insights on environmental issuesWebsiteEco Expo Asia: www.ecoexpoasia.comMedia enquiriesPlease contact the HKTDC’s Communications and Public Affairs Department:Stanley SoTel: (852) 2584 4049Email: stanley.hp.so@hktdc.orgClayton Lauw Tel: (852) 2584 4472 Email: clayton.y.lauw@hktdc.orgThe HKTDC’s Media Room: http://mediaroom.hktdc.com/enAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in the Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. About Messe FrankfurtThe Messe Frankfurt Group is one of the world’s leading trade fair, congress and event organisers with its own exhibition grounds. With a workforce of some 2,160 people at its headquarters in Frankfurt am Main and in 28 subsidiaries, it organises events around the world. Group sales in financial year 2022 were around €454 million. We serve our customers’ business interests efficiently within the framework of our Fairs & Events, Locations and Services business fields. One of Messe Frankfurt’s key strengths is its powerful and closely knit global sales network, which covers around 180 countries in all regions of the world. Our comprehensive range of services – both onsite and online – ensures that customers worldwide enjoy consistently high quality and flexibility when planning, organising and running their events. We are using our digital expertise to develop new business models. The wide range of services includes renting exhibition grounds, trade fair construction and marketing, personnel and food services. Sustainability is a central pillar of our corporate strategy. Here, we strike a healthy balance between ecological and economic interests, social responsibility and diversity.For more information, please visit our website at: www.messefrankfurt.com/sustainability. With its headquarters in Frankfurt am Main, the company is owned by the City of Frankfurt (60%) and the State of Hesse (40%). For more information, please visit our website at: www.messefrankfurt.com Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
Radisson Step-Out Drilling at O’Brien Gold Project Intersects High-Grade Mineralization in Multiple Locations ACN Newswire

Radisson Step-Out Drilling at O’Brien Gold Project Intersects High-Grade Mineralization in Multiple Locations

Rouyn-Noranda, Quebec--(ACN Newswire via SeaPRwire.com - October 28, 2025) - Radisson Mining Resources Inc. (TSXV: RDS) (OTCQX: RMRDF) ("Radisson" or the "Company") is pleased to announce assay results from fifteen new drill holes completed at its 100%-owned O'Brien Gold Project ("O'Brien" or the "Project") located in the Abitibi region of Québec. The fifteen holes represent step-outs below the existing geological model and the historic O'Brien Gold Mine and are part of an ongoing 140,000-metre drill program designed to test the overall scope of gold mineralization at the Project (see Radisson news release dated October 16, 2025). All holes intersected gold mineralization in characteristic quartz-sulphide-gold veins within alteration zones, and thirteen of the holes returned intercepts with grades and thicknesses consistent with the Project's existing mineral resources.Today's results include significant intercepts in three separate step-out locations (Figures 1 & 2), each of which has significance for the potential future growth of the Project's mineral resources. These are:Between Trends #1 and #2 at 1,000 Metres Vertical DepthOB-25-371W5 intersected 10.50 grams per tonne ("g/t") gold ("Au") over 6.5 metres, including 14.90 g/t Au over 1.5 metres and including 16.95 g/t Au over 1.0 metreOB-25-371W4 intersected 11.25 g/t Au over 2.5 metres, including 17.80 g/t Au over 1.5 metresOB-25-371W6 intersected 4.51 g/t Au over 9.0 metres, including 10.70 g/t Au over 1.5 metresBeneath the Historic "O'Brien Mine West" at 1,000 Metres Vertical Depth OB-25-376W1 intersected 9.16 g/t Au over 2.5 metres, including 14.70 g/t Au over 1.1 metresOB-25-376 intersected 8.05 g/t Au over 2.50 metres, including 15.75 g/t Au over 1.0 metreBeneath the Historic "O'Brien Mine" at 1,100 Metres Vertical DepthOB-24-337W11 intersected 7.00 g/t Au over 3.0 metres, including 12.60 g/t Au over 1.5 metres, and 13.00 g/t Au over 1.50 metresMatt Manson, President & CEO, commented: "Today's drill results illustrate the extension of classic, high-grade O'Brien gold mineralization across a broad front. We are reporting the first high-grade intercepts beneath the western portion of the historic mine, with drill hole OB-25-376W1 extending mineralization 160 metres below the former mine in this area. Drill hole OB-24-337W11 demonstrates continuity of high-grade mineralization below the main stope of the historic mine. Of particular note, drill holes OB-25-371W4 to W6 returned high-grade mineralization on the western edge of the deep extension of Trend #2, close to the observed extension of Trend #1 (Figures 1&2). This suggests that the apparent gap between these two trends is a function of drill coverage rather than geology, as we have suspected. Closing this gap with new drilling is a priority. With a fully-funded 140,000-metre drill program ongoing and an increase in rigs from the current four to an eventual eight, we are casting a wide net at O'Brien and seeing consistent success."Figure 1: Longitudinal Vertical Section and Plan View of Gold Vein Mineralization and Mineral Resources at the O'Brien Gold Project, with Today's Drill Holes IllustratedTo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_002full.jpgNotes on Calculation of Drill Intercepts:The O'Brien Gold Project Mineral Resource Estimate effective May 6, 2025 ("MRE") utilizes a 2.20 g/t Au bottom cut-off, a US$2,000 gold price, a minimum mining width of 1.2 metres, and a 40 g/t Au upper cap on composites. Intercepts presented in Table 1 are calculated with a 3.00 g/t Au bottom cut-off. True widths, based on depth of intercept and drill hole inclination, are estimated to be 30-80% of core length. Table 2 presents additional drill intercepts calculated with a 1.00 g/t bottom cut-off over a minimum 1.0 metre core length so as to illustrate the frequency and continuity of mineralized intervals within which high-grade gold veins at O'Brien are developed. Lithology Codes: PON-S3: Pontiac Sediments; V3-S, V3-N, V3-CEN: Basalt-South, North, Central; S1P, S3P: Conglomerate; POR-S, POR-N: Porphyry South, North; TX: Crystal Tuff; ZFLLC: Larder Lake-Cadillac Fault Zone.Figure 2: Longitudinal Vertical Section of Gold Vein Mineralization and Mineral Resources at the O'Brien Gold Project, with Deep Step-Out Drill Holes Completed and/or Published by the Company since December 2024. To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_004full.jpgGold Mineralization at O'BrienGold mineralizing quartz-sulphide veins at O'Brien occur within a thin band of interlayered mafic volcanic rocks, conglomerates, and porphyritic andesitic sills of the Piché Group occurring in contact with the east-west oriented Larder Lake-Cadillac Break ("LLCB"). Gold, along with pyrite and arsenopyrite, is typically associated with shearing and a pervasive biotite alteration, and developed within multiple Piché Group lithologies and, occasionally, the hanging-wall Pontiac and footwall Cadillac meta-sedimentary rocks.As mapped at the historic O'Brien mine, and now replicated in the modern drilling, individual veins are generally narrow, ranging from several centimetres up to several metres in thickness. Multiple veins occur sub-parallel to each other, as well as sub-parallel to the Piché lithologies and the LLCB. Individual veins have well-established lateral continuity, with near-vertical, high-grade shoots developed over significant lengths. Based on the historic data available, it is clear that the former mine was "high-graded", with mining focussed on a main central stope and parallel veins identified but left undeveloped.The historic O'Brien mine produced over half a million ounces of gold from such veins and shoots at an average grade exceeding 15 g/t Au and over a vertical extent of at least 1,000 metres. Modern exploration has focussed on delineating well developed vein mineralization to the east of the historic mine, with additional high-grade shoots becoming evident in the exploration data over what has been described as a series of repeating trends ("Trend #s 0 to 5").Step-Out Drilling at O'BrienSince the end of 2024, Radisson has been pursuing a program of broad step-outs beneath the historic O'Brien Gold mine and the existing mineral resources designed to test the extent of mineralization at the Project. This drilling is accomplished with pilot holes followed by wedges and directional drilling to maximize drill efficiency. On October 16, 2025 Radisson announced the expansion of the step-out drill program to 140,000 metres employing an eventual eight drill rigs.The origin of the step-out drill program was the deep pilot hole OB-24-337, which was the first exploration drill hole located below the former mine workings since mining ended in 1957. This hole intersected 31.24 g/t Au over 8.0 metres, including 242.0 g/t Au over 1.0 metre at approximately 1,500 metres vertical depth (see Radisson news release dated December 16, 2024). With today's results, assay results from a total of 11 wedges from OB-24-337 have now been reported and up to six gold-bearing veins have been delineated over an area of approximately 250 metres (east-west) by 500 metres (vertical). Included in today's results is the eleventh wedge, OB24-337-W11, which intersected 7.00 g/t Au over 3.0 metres, including 12.60 g/t Au over 1.5 metres, and 13.00 g/t Au over 1.50 metres approximately 100 metres below the final historic mining stope (Figure 1). This serves to demonstrate the continuity of mineralization from the former mine downwards towards the cluster previously published wedges (Figures 1 & 2; see Radisson news release dated July 16, 2025). Current drilling in this area is focussed on infilling with pilot holes and wedge extensions both above and below the OB-24-337 pattern of wedge branches to test the full continuity of mineralization from the historic mine down to 2 kilometres depth.Step-out drilling with wedge branches has also confirmed high-grade mineralization 170 metres below the base of the existing mineral resources at Trend #1 and 300 metres at Trend #2. These have included pilot hole OB-24-324, which intersected 27.61 g/t Au over 6.0 metres at Trend #1 (see Radisson news release dated October 30, 2024) and OB-24-363, which intersected 8.41 g/t Au over 2.20 metres, including 14.40 g/t Au over 1.20 metres and 9.07 g/t Au over 1.80 metres, including 12.10 g/t Au over 0.90 metres at Trend #2 (see Radisson news release dated September 8, 2025). Today's results include six wedges from drill hole OB-25-371, which demonstrate strongly developed, high-grade mineralization on the western edge of the deep extension of Trend #2. These holes include OB-25-371W5, which intersected 10.50 g/t Au over 6.5 metres, including 14.90 g/t Au over 1.5 metres and including 16.95 g/t Au over 1.0 metre (Figures 1&3). The significance of these holes is that the apparent separation of Trend #1 and Trend #2 is based, in part, on a data gap caused by drill rig access restrictions and a lack of drilling (Figure 2). Targeting this gap and testing for continuity of mineralization between Trends #1 and #2, as well as at depth, is a priority of the current drill program.Today's results also include the first drill holes located below the western portion of the historic O'Brien Gold Mine, designated "O'Brien Mine West". As with the main mining area, no exploration had been conducted below O'Brien Mine West since operations ended in 1957. From pilot hole OB-25-376 and wedge branches W1 to W5, five holes returned intercepts with grades and thicknesses consistent with the Project's mineral resources, including OB-25-376W1, which intersected 9.16 g/t Au over 2.5 metres, including 14.70 g/t Au over 1.1 metres (Figure 1). This now extends gold mineralization at O'Brien Mine West 160 metres below the base of the former mine workings (Figure 4).Figure 3: Vertical Cross Section through "Trend #2" with Drill Hole Wedges OB-25-371W2 to W6To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_005full.jpg Figure 4: Vertical Cross Section through "O'Brien Mine West" with Drill Hole OB-25-376 and Wedges W1 to W5To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_006full.jpgQA/QCAll drill cores in this campaign are NQ in size. Assays were completed on sawn half-cores, with the second half kept for future reference. The samples were analyzed using standard fire assay procedures with Atomic Absorption (AA) finish at ALS Laboratory Ltd, in Val-d'Or, Quebec. Samples yielding a grade higher than 10 g/t Au were analyzed a second time by fire assay with gravimetric finish at the same laboratory. Mineralized zones containing visible gold were analyzed with metallic sieve procedure. Standard reference materials, blank samples and duplicates were inserted prior to shipment for quality assurance and quality control (QA/QC) program.Qualified Persons Disclosure of a scientific or technical nature in this news release was prepared under the supervision of Mr. Richard Nieminen, P.Geo, (QC), a geological consultant for Radisson and a Qualified Person for purposes of NI 43-101. Mr. Luke Evans, M.Sc., P.Eng., ing, of SLR Consulting (Canada) Ltd., is the Qualified Person responsible for the preparation of the MRE at O'Brien. Each of Mr. Nieminen and Mr. Evans is independent of Radisson and the O'Brien Gold Project.About Radisson MiningRadisson is a gold exploration company focused on its 100% owned O'Brien Gold Project, located in the Bousquet-Cadillac mining camp along the world-renowned Larder-Lake-Cadillac Break in Abitibi, Québec. A July 2025 Preliminary Economic Assessment described a low cost and high value project with an 11-year mine life and significant upside potential based on the use of existing regional infrastructure. Indicated Mineral Resources are estimated at 0.58 million ounces (2.20 million tonnes at 8.2 g/t Au), with additional Inferred Mineral Resources estimated at 0.93 million ounces (6.67 million tonnes at 4.4 g/t Au). Please see the NI 43-101 "O'Brien Gold Project Technical Report and Preliminary Economic Assessment, Québec, Canada" effective June 27, 2025, and other filings made with Canadian securities regulatory authorities available at www.sedarplus.ca for further details and assumptions relating to the O'Brien Gold Project. For more information on Radisson, visit our website at www.radissonmining.com or contact:Matt MansonPresident and CEO416.618.5885mmanson@radissonmining.comKristina PillonManager, Investor Relations604.908.1695kpillon@radissonmining.comForward-Looking StatementsThis news release contains "forward-looking information" within the meaning of the applicable Canadian securities legislation that is based on expectations, estimates, projections, and interpretations as at the date of this news release. Forward-looking statements including, but are not limited to, statements with respect to the ability to execute the Company's plans relating to the O'Brien Gold Project as set out in the Preliminary Economic Assessment; the Company's ability to complete its planned exploration and development programs; the absence of adverse conditions at the O'Brien Gold Project; the absence of unforeseen operational delays; the absence of material delays in obtaining necessary permits; the price of gold remaining at levels that render the O'Brien Gold Project profitable; the Company's ability to continue raising necessary capital to finance its operations; the ability to realize on the mineral resource and mineral reserve estimates; assumptions regarding present and future business strategies; local and global geopolitical and economic conditions and the environment in which the Company operates and will operate in the future; planned and ongoing drilling; the significance of drill results; the ability to continue drilling; the impact of drilling on the definition of any resource; and the ability to incorporate new drilling in an updated technical report and resource modelling; the Company's ability to grow the O'Brien Gold Project; and the ability to convert inferred mineral resources to indicated mineral resources. Any statement that involves discussions with respect to predictions, expectations, interpretations, beliefs, plans, projections, objectives, assumptions, future events or performance (often but not always using phrases such as "expects", or "does not expect", "is expected", "interpreted", "management's view", "anticipates" or "does not anticipate", "plans", "budget", "scheduled", "forecasts", "estimates", "believes" or "intends" or variations of such words and phrases or stating that certain actions, events or results "may" or "could", "would", "might" or "will" be taken to occur or be achieved) are not statements of historical fact and may be forward-looking information and are intended to identify forward-looking information. Except for statements of historical fact relating to the Company, certain information contained herein constitutes forward-looking statements Forward-looking information is based on estimates of management of the Company, at the time it was made, involves known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of the companies to be materially different from any future results, performance or achievements expressed or implied by such forward-looking information. Such factors include, among others; the risk that the O'Brien Gold Project will never reach the production stage (including due to a lack of financing); the Company's capital requirements and access to funding; changes in legislation, regulations and accounting standards to which the Company is subject, including environmental, health and safety standards, and the impact of such legislation, regulations and standards on the Company's activities; price volatility and availability of commodities; instability in the global financial system; the effects of high inflation, such as higher commodity prices; the risk of any future litigation against the Company; changes in project parameters and/or economic assessments as plans continue to be refined; the risk that actual costs may exceed estimated costs; geological, mining and exploration technical problems; failure of plant, equipment or processes to operate as anticipated; accidents, labour disputes and other risks of the mining industry; delays in obtaining governmental approvals or financing; risks relating to the drill results at O'Brien; the significance of drill results; and the ability of drill results to accurately predict mineralization. Although the forward-looking information contained in this news release is based upon what management believes, or believed at the time, to be reasonable assumptions, the parties cannot assure shareholders and prospective purchasers of securities that actual results will be consistent with such forward-looking information, as there may be other factors that cause results not to be as anticipated, estimated or intended, and neither the Company nor any other person assumes responsibility for the accuracy and completeness of any such forward-looking information. The Company believes that this forward-looking information is based on reasonable assumptions, but no assurance can be given that these expectations will prove to be correct and such forward-looking statements included in this press release should not be unduly relied upon. The Company does not undertake, and assumes no obligation, to update or revise any such forward-looking statements or forward-looking information contained herein to reflect new events or circumstances, except as may be required by law. These statements speak only as of the date of this news release.Please refer to the "Risks and Uncertainties Related to Exploration" and the "Risks Related to Financing and Development" sections of the Company's Management's Discussion and Analysis dated April 29, 2025 for the year ended December 31, 2024, and the Company's Management's Discussion and Analysis dated August 27, 2025 for the three-month period ended June 30, 2025, all of which are available electronically on SEDAR+ at www.sedarplus.ca. All forward-looking statements contained in this press release are expressly qualified by this cautionary statement.Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release. No stock exchange, securities commission or other regulatory authority has approved or disapproved the information contained herein.To view the source version of this press release, please visit https://www.newsfilecorp.com/release/272164 Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More
康哲藥業(867.HK; 8A8.SG)簽訂眼科藥物諾適得(R)與倍優適(R)經銷協議 ACN Newswire

康哲藥業(867.HK; 8A8.SG)簽訂眼科藥物諾適得(R)與倍優適(R)經銷協議

深圳, 2025年10月27日 - (亞太商訊 via SeaPRwire.com) - 康哲藥業控股有限公司(「康哲藥業」)欣然宣佈,於2025年10月27日,康哲藥業通過子公司CMS VISION INTERNATIONAL MANAGEMENT LIMITED與Novartis Pharma Services AG (「諾華」)就雷珠單抗注射液(「諾適得(R)」)、布西珠單抗注射液(「倍優適(R)」)簽訂經銷協議(「協議」)。根據協議,康哲藥業獲得產品在中華人民共和國(為協議之目的,不含香港特別行政區、澳門特別行政區、台灣)的協議所約定之獨家進口、經銷、銷售、推廣權利;諾華繼續負責生產、供應產品。合作期限為協議約定的生效日起五年。兩款合作產品均已在中國獲批上市,其中諾適得(R)是中國首個獲批用於眼科的抗血管內皮生長因子(VEGF)藥物,具備成熟的臨床應用經驗,為眾多眼底疾病患者提供了可靠保障;諾適得(R)已被批准用於治療濕性年齡相關性黃斑變性(nAMD)、糖尿病性黃斑水腫(DME)、視網膜靜脈阻塞(RVO)繼發的黃斑水腫等多項眼底新生血管性疾病。另一款產品倍優適(R)為新一代抗VEGF藥物,2025年5月中國獲批用於DME,其憑藉獨特的超小分子(僅26kDa)、高濃度創新優勢,顯著改善視網膜解剖學結構,助力更多DME患者獲得視力改善,減輕治療負擔。康哲藥業眼科業務公司「康哲維盛」專注於在全球範圍內佈局、開發臨床急需的眼科藥械創新產品,致力於打造「中國眼科醫藥龍頭」,此次合作將提升康哲維盛在眼科領域的整體競爭力。康哲維盛已覆蓋眼底疾病、視疲勞、青光眼等眼科疾病領域,諾適得(R)及倍優適(R)加入後,將與在售獨家藥施圖倫滴眼液(七葉洋地黃雙苷滴眼液)、在售獨家醫療器械EyeOP1青光眼治療儀在客戶、專家資源、渠道網絡上產生高度協同,提升康哲維盛在眼科領域的學術品牌競爭力,為持續合作、開發臨床急需的眼科創新產品帶來正向推動作用,為眼科疾病患者提供更多元化的治療選擇。同時康哲維盛專業的眼科團隊將整合市場渠道與學術資源,提升團隊整體效能,並預期對康哲藥業業績產生積極正面影響。關於諾適得(R)及眼底新生血管性疾病的更多信息諾適得(R)是重組抗VEGF人源化單克隆抗體Fab片段,靶向抑制人血管內皮生長因子A(VEGF-A),以抑制血管內皮細胞增殖、新生血管生成和血管滲漏。諾適得(R)作為中國首個獲批用於眼科的抗VEGF藥物[3],自2011年在中國上市以來,已被批准用於治療多項眼底新生血管性疾病,包括nAMD、DME、RVO繼發的黃斑水腫、脈絡膜新生血管(CNV)、糖尿病視網膜病變(DR)、早產兒視網膜病變(ROP)。諾適得(R)已於2017年被納入《國家基本醫療保險、工傷保險和生育保險藥品目錄》,具備成熟的臨床應用經驗,為眾多眼底疾病患者提供了可靠保障。眼底新生血管性疾病是一類以血管通透性增加、血管滲漏以及血管完整性的缺失為特徵的嚴重致盲性眼病,主要包括nAMD、DR、DME、RVO、CNV、ROP等。抗VEGF藥物是多個權威指南推薦治療眼底新生血管性疾病的一線療法[3, 4]。根據弗若斯特沙利文報告,中國眼底新生血管性疾病患者預計將從2019年的47.8百萬人增至2030年的61.2百萬人。中國抗VEGF眼科藥物市場預期將從2019年的24億元增長至2030年的186億元。根據《抗VEGF藥物治療眼底新生血管性疾病》,諾適得(R)作為中國首個獲批用於治療眼底新生血管性疾病的抗VEGF藥物,在多項臨床試驗中均顯示出良好的安全性和有效性,已被廣泛應用於治療眼底新生血管性疾病,它的問世代表了眼科臨床治療的一個重大進步[5]。關於倍優適(R)及DME適應症的更多信息倍優適(R)是一種靶向VEGF-A的新型人源化單鏈抗體片段,已於2025年5月獲得中國國家藥品監督管理局批准用於DME。作為目前分子量最小的抗VEGF藥物(僅26kDa),倍優適(R)治療DME負荷期每6周給藥一次(其他抗VEGF藥物負荷期每4周給藥1次),維持期每2至3個月給藥一次。倍優適(R)針對初治DME患者的全球3期KESTREL和KITE研究均達到主要療效終點且視力獲益持續至100周。倍優適(R)6mg組患者IRF(視網膜內積液)和/或SRF(視網膜下積液)更少。倍優適(R)首年中位注射次數(7次)少於阿柏西普(9次),同時總體安全性與後者相當[6]。中國真實世界研究BEST研究顯示,經治不達標的DME患者經倍優適(R)首針治療1周後BCVA即較基線提升6.1字母,注射第3針(12周)提升10字母,倍優適(R)為經治DME提供更優化的治療選擇[7]。DME是由於黃斑區毛細血管滲漏所致的視網膜增厚,是血視網膜屏障破壞的結果,主要影響中心視力[8]。據弗若斯特沙利文報告,2025年中國約有7.89百萬例DME患者。但即使按目前規範的抗VEGF藥物治療方案,仍有約30%-50%DME患者積液控制不佳[9-11]。《2022中國常見眼底病慢病管理現狀白皮書》調研顯示,我國患者治療依從性較差,30%以上DME患者未能完成負荷期治療。臨床亟需更強效、更持久、依從性更高的治療藥物以改善DME患者的診療現狀。新一代抗VEGF藥物倍優適(R)為解決這一難題提供了潛在方法,其憑藉獨特的超小分子、高濃度創新優勢,顯著改善視網膜解剖學結構,助力更多DME患者獲得視力改善,減輕治療負擔。關於諾華諾華是一家全球知名的醫藥企業,總部位於瑞士巴塞爾。諾華聚焦患者需求緊迫的四大核心治療領域(心血管、腎臟及代謝,腫瘤,免疫,神經科學)以及五大關鍵技術平台(化學療法、生物療法、xRNA療法、放射配體療法、基因和細胞療法)。關於康哲藥業康哲藥業是一家鏈接醫藥創新與商業化,把控產品全生命週期管理的開放式平台型企業,致力於提供有競爭力的產品和服務,滿足尚未滿足的醫療需求。康哲藥業專注於全球首創(FIC)及同類最優(BIC)的創新產品,並高效推進創新產品臨床研究開發和商業化進程,賦能科研成果向診療實踐的持續轉化,造福患者。康哲藥業聚焦專科領域,擁有被驗證的商業化能力,廣泛的渠道覆蓋和多疾病領域專家資源,核心在售產品已獲領先的學術與市場地位。康哲藥業圍繞優勢專科領域不斷縱深發展,以鞏固心腦血管/消化/眼科/皮膚健康業務競爭力,帶來專科規模效率,其中皮膚健康業務(德鎂醫藥)已成為其細分領域的龍頭企業,並擬於聯交所獨立上市。同時,康哲藥業持續推動研產銷全產業鏈在東南亞及中東區域運營發展,以獲取新興市場的增量,助力集團實現高質量可持續發展。參考文獻/資料1. 產品相關信息可在諾華官網查詢,網址:https://www.novartis.com.cn/news/big-news-noxtex-welcomes-the-approval-of-dual-indications2. Lim, Jennifer I et al. “Diabetic Retinopathy Preferred Practice Pattern(R).” Ophthalmology vol. 132,4 (2025): P75-P162. doi:10.1016/j.ophtha.2024.12.0203. 中華醫學會眼科學分會眼底病學組,中國醫師協會眼科醫師分會眼底病學組.中國年齡相關性黃斑變性臨床診療指南(2023年)[J].中華眼科雜誌,2023,59(5):347-366.4. 許迅,王建影.疾病譜變化驅動臨床藥物更迭[N].健康報,2023-07-05(005).5. 侯慧敏,常雪柯,靳雨佳,等.抗VEGF藥物治療眼底新生血管性疾病[J].國際眼科縱覽,2024,48(6):464-470.6. Wykoff CC, Garweg JG, Regillo C, et al. KESTREL and KITE Phase 3 Studies: 100-Week Results With Brolucizumab in Patients With Diaßbetic Macular Edema. Am J Ophthalmol. 2024;260:70-83.7. 餘洪華,2025中國眼底病論壇暨國際視網膜研討會,6月4日-7日,中國無錫8. 中華醫學會眼科學分會眼底病學組,中國醫師協會眼科醫師分會眼底病學組. 我國糖尿病視網膜病變臨床診療指南(2022年)[J]. 中華眼底病雜誌,2023,39(2):99-124.9. 戴虹, 盧穎毅. 糖尿病黃斑水腫治療策略的變化與面臨的問題[J].中華眼底病雜誌, 2022, 38(1): 6-9.10. Bressler, Neil M et al. “Persistent Macular Thickening Following Intravitreous Aflibercept, Bevacizumab, or Ranibizumab for Central-Involved Diabetic Macular Edema With Vision Impairment: A Secondary Analysis of a Randomized Clinical Trial.” JAMA ophthalmology vol. 136,3 (2018): 257-269.11. Chatziralli, I et al. “Identification of time point to best define 'sub-optimal response' following intravitreal ranibizumab therapy for diabetic macular edema based on real-life data.” Eye (London, England) vol. 31,11 (2017): 1594-1599.康哲藥業免責與前瞻性聲明本新聞無意向您做任何產品的推廣,非廣告用途。本新聞不對任何藥品和醫療器械和/或適應症作推薦。若您想瞭解具體疾病診療資訊,請遵從醫生或其他醫療衛生專業人士的意見或指導。醫療衛生專業人士作出的任何與治療有關的決定應根據患者的具體情況並遵照藥品說明書。由康哲藥業編制的此新聞不構成購買或認購任何證券的任何要約或邀請,不形成任何合約或任何其他約束性承諾的依據或加以依賴。本新聞由康哲藥業根據其認為可靠之資料及數據編制,但康哲藥業並無進行任何說明或保證、明述或暗示,或其他表述,對本新聞內容的真實性、準確性、完整性、公平性及合理性不應加以依賴。本新聞中討論的若干事宜可能包含涉及康哲藥業的市場機會及業務前景的陳述,該等陳述分別或統稱為前瞻性聲明。該等前瞻性聲明並非對未來表現的保證,存在已知及未知的風險、不明朗性及難以預知的假設。康哲藥業並不採納本新聞包含的第三方所做的任何前瞻性聲明及預測,康哲藥業對該等第三方聲明及預測不承擔責任。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
More